Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27144742 | 1.00 | CDC7 (0.54) | CDC7CDK2MAPTPARP1PIP4K2A | |
| SCHEMBL2294384 | 0.89 | CDC7 (0.53) | CDC7CDK2MAPTPARP1KDM4E | |
| SCHEMBL20603929 | 0.82 | CDC7 (0.58) | CDC7CDK2MAPTPARP1ALDH1A1 | |
| SCHEMBL2295440 | 0.81 | CDC7 (0.56) | CDC7CDK2PARP1KDM4EMKNK2 | |
| SCHEMBL28545337 | 0.81 | HPGD (0.52) | CDC7CDK2MAPTPARP1ALDH1A1 | |
| SCHEMBL28650970 | 0.81 | CDC7 (0.47) | CDC7CDK2PARP1ALDH1A1ATM | |
| SCHEMBL31070284 | 0.81 | HPGD (0.52) | CDC7CDK2MAPTPARP1ALDH1A1 | |
| SCHEMBL1150333 | 0.80 | CDC7 (0.54) | CDC7CDK2PARP1ALDH1A1KDM4E | |
| SCHEMBL30828406 | 0.80 | CDC7 (0.54) | CDC7CDK2PARP1ALDH1A1KDM4E | |
| SCHEMBL23413110 | 0.79 | MKNK2 (0.58) | MAPTPIP4K2APIK3CGMKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112424201-B | Protein kinase inhibitors that promote liver regeneration or reduce or prevent hepatocyte death | 海帕瑞吉尼克斯股份有限公司 | 2024-04-02 | — | — | CN | disclosed |