Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22338052 | 0.79 | TP53 (0.44) | CACNA2D1CACNA1BCACNB1MEN1KMT2A | |
| SCHEMBL21969930 | 0.78 | KDM4E (0.42) | CACNA2D1CACNA1BCACNB1MEN1KMT2A | |
| SCHEMBL374605 | 0.78 | MTNR1A (0.53) | CACNA2D1CACNA1BCACNB1MEN1KMT2A | |
| SCHEMBL22485411 | 0.76 | CYP2C19 (0.47) | MEN1KMT2ANPC1MAPTPOLB | |
| SCHEMBL3105534 | 0.76 | MTNR1A (0.52) | CACNA2D1CACNA1BCACNB1MEN1KMT2A | |
| SCHEMBL21969562 | 0.75 | MEN1 (0.40) | CACNA2D1CACNA1BCACNB1MEN1KMT2A | |
| SCHEMBL23758985 | 0.75 | CACNA2D1 (0.37) | CACNA2D1CACNA1BCACNB1MEN1KMT2A | |
| SCHEMBL22485571 | 0.75 | PYCR1 (0.43) | MEN1KMT2ALMNASMN1; SMN2NPC1 | |
| SCHEMBL22485470 | 0.75 | CYP2C19 (0.46) | MEN1KMT2ANPC1MAPTTSHR | |
| SCHEMBL22485618 | 0.74 | ESR1 (0.39) | MEN1KMT2ASMN1; SMN2GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074885-B | Boronic acid derivatives | 默克专利股份公司 | 2020-11-27 | — | — | CN | disclosed |