SCHEMBL28545644

SCHEMBL28545644

CCCC(O)CCOC(=O)c1ccc(C(=O)OCCC(O)CCC)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.56
ESR1 P03372 3/20 0.56
ALDH1A1 P00352 3/20 0.56
CHRM1 P11229 1/20 0.56
SLC6A2 P23975 1/20 0.56
KDR P35968 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
LMNA P02545 5/20 0.53
CYP1A2 P05177 4/20 0.53
CYP2C19 P33261 2/20 0.53
MAPK1 P28482 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
CYP2D6 P10635 2/20 0.53
NR1H2 P55055 1/20 0.53
RNASEL Q05823 1/20 0.53
CYP3A4 P08684 3/20 0.51
CYP2C9 P11712 1/20 0.51
PDE4D Q08499 1/20 0.51
PKM P14618 1/20 0.49
HSD17B10 Q99714 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23926207 0.90 LMNA (0.58) TSHRESR1ALDH1A1CHRM1SLC6A2
SCHEMBL23926202 0.90 LMNA (0.58) TSHRESR1ALDH1A1CHRM1SLC6A2
SCHEMBL23926236 0.88 TSHR (0.57) TSHRESR1ALDH1A1CHRM1SLC6A2
SCHEMBL23926201 0.87 TSHR (0.53) TSHRESR1ALDH1A1CHRM1SLC6A2
SCHEMBL3093193 0.84 MAPK1 (0.46) TSHRESR1ALDH1A1CHRM1SLC6A2
SCHEMBL23926231 0.84 ADRB2 (0.54) TSHRESR1ALDH1A1CHRM1SLC6A2
SCHEMBL23926217 0.83 LMNA (0.63) TSHRESR1ALDH1A1CHRM1SLC6A2
SCHEMBL15178132 0.82 LMNA (0.63) TSHRESR1ALDH1A1CHRM1SLC6A2
SCHEMBL1263574 0.82 ESR1 (0.66) TSHRESR1ALDH1A1CHRM1SLC6A2
SCHEMBL23926233 0.81 TSHR (0.61) TSHRESR1ALDH1A1CHRM1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689727-B Process for the regioselective synthesis of polyesters from asymmetric diols 维尔萨利斯股份公司 2020-12-01 CN disclosed