SCHEMBL28545665

SCHEMBL28545665

O=C(O)Oc1ccc(-c2ccccc2)c2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.42
KMT2A Q03164 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
HSD17B10 Q99714 2/20 0.41
MEN1 O00255 1/20 0.41
JAK2 O60674 1/20 0.41
USP2 O75604 1/20 0.41
ESR1 P03372 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
ALOX15 P16050 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ESR2 Q92731 1/20 0.41
TSHR P16473 2/20 0.40
PKM P14618 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
HTR6 P50406 1/20 0.40
BACE1 P56817 2/20 0.39
PTGDR2 Q9Y5Y4 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10578343 0.90 ESR1 (0.44) KMT2ANPSR1HSD17B10MEN1JAK2
SCHEMBL2638148 0.88 ESR1 (0.48) KMT2ANPSR1HSD17B10MEN1JAK2
SCHEMBL2834876 0.79 ESR1 (0.53) KMT2ANPSR1HSD17B10MEN1JAK2
SCHEMBL19244671 0.78 CDC25B (0.56) KMT2ANPSR1HSD17B10ESR1MAPT
Naphthalene SCHEMBL1132213 0.78 HSD17B10 (0.55) KMT2ANPSR1HSD17B10MEN1JAK2
SCHEMBL1639323 0.78 FABP3 (0.56) HSD17B10USP2MAPTSMN1; SMN2RAB9A
SCHEMBL30563023 0.78 FABP3 (0.56) HSD17B10USP2MAPTSMN1; SMN2RAB9A
SCHEMBL6664394 0.77 TSHR (0.44) KMT2ANPSR1HSD17B10MEN1JAK2
SCHEMBL28659172 0.77 CYP2D6 (0.42) CYP2D6KMT2AHSD17B10MEN1MAPT
SCHEMBL238322 0.76 MCL1 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114746488-A Films with special properties 科思创知识产权两合公司 2022-07-12 CN disclosed
CN-113242795-A Plastic film with high opacity and low transparency for identification documents with transparent window 科思创知识产权两合公司 2021-08-10 CN disclosed
CN-113056369-A Method for producing a laminate comprising electronic components and/or functional units 科思创知识产权两合公司 2021-06-29 CN disclosed
CN-112654508-A Improved method for locally coloring plastic parts 科思创知识产权两合公司 2021-04-13 CN disclosed
CN-111479692-A Plastic film for identification documents with better brightness of the embossed hologram 科思创德国股份有限公司 2020-07-31 CN disclosed