Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2638148 | 0.88 | ESR1 (0.48) | TSHRPKMNPC1RAB9AKMT2A | |
| SCHEMBL484956 | 0.83 | HTT (0.51) | TSHRPKMNPC1RAB9AKMT2A | |
| SCHEMBL10578343 | 0.82 | ESR1 (0.44) | TSHRPKMNPC1RAB9AKMT2A | |
| SCHEMBL2834876 | 0.79 | ESR1 (0.53) | RAB9AKMT2AMEN1ESR1NPSR1 | |
| SCHEMBL19244671 | 0.78 | CDC25B (0.56) | PKMKMT2AESR1NPSR1ESR2 | |
| Naphthalene SCHEMBL1132213 | 0.78 | HSD17B10 (0.55) | RAB9AKMT2AMEN1ESR1NPSR1 | |
| SCHEMBL18697312 | 0.77 | TSHR (0.46) | TSHRPKMNPC1RAB9AKMT2A | |
| SCHEMBL28545665 | 0.77 | CYP2D6 (0.42) | TSHRPKMNPC1RAB9AKMT2A | |
| SCHEMBL57244 | 0.75 | FAAH (0.51) | NPC1KMT2AGAASMN1; SMN2MAPT | |
| SCHEMBL29721956 | 0.74 | L3MBTL1 (0.51) | TSHRKMT2AMEN1NPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0952154-B1 | N-acyl and N-aroyl aralkyl amides | PFIZER PROD INC (US) | 2004-08-18 | — | — | EP | claimed |