SCHEMBL238322

SCHEMBL238322

O=C(O)Oc1ccc(-c2cccc3ccccc23)cc1-c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 3/20 0.52
ACMSD Q8TDX5 1/20 0.52
PPARG P37231 9/20 0.49
PPARA Q07869 9/20 0.49
CYP2C9 P11712 2/20 0.49
CYP2C19 P33261 2/20 0.49
PPARD Q03181 1/20 0.49
EDNRB P24530 1/20 0.48
EDNRA P25101 1/20 0.48
CYP1A2 P05177 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48
SLC6A9 P48067 1/20 0.47
CA12 O43570 2/20 0.45
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
CA9 Q16790 2/20 0.45
CHRNB2 P17787 1/20 0.42
CHRNB4 P30926 1/20 0.42
CHRNA3 P32297 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL28016110 0.99 MCL1 (0.51) MCL1ACMSDPPARGPPARACYP2C9
SCHEMBL238320 0.88 PPARG (0.54) MCL1ACMSDPPARGPPARACYP2C9
Bicarbonate SCHEMBL28016109 0.87 PPARG (0.52) MCL1ACMSDPPARGPPARACYP2C9
SCHEMBL17697651 0.81 SLC6A9 (0.51) MCL1ACMSDSLC6A9
SCHEMBL236489 0.81 ACMSD (0.46) ACMSDHDAC8SLC6A9
SCHEMBL30356799 0.80 PPARG (0.62) MCL1ACMSDPPARGPPARACYP2C9
SCHEMBL27609367 0.80 PPARG (0.55) MCL1ACMSDPPARGPPARACYP2C9
SCHEMBL17942333 0.80 PPARG (0.62) MCL1ACMSDPPARGPPARACYP2C9
SCHEMBL5873749 0.80 NCEH1 (0.39) SLC6A9CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL2291368 0.80 ALDH1A1 (0.49) MCL1ACMSDPPARGPPARACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2593288-B2 APPARATUS AND PROCESS FOR PRODUCING PRODUCTS FROM PIGMENT-CONTAINING POLYMER MIXTURES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2025-04-16 EP disclosed
US-20210371609-A1 PLASTIC FILMS WITH REDUCED UV ACTIVITY COVESTRO LLC 2021-12-02 US disclosed
EP-3707198-B1 PLASTIC FILMS WITH REDUCED UV ACTIVITY COVESTRO DEUTSCHLAND AG (DE) 2021-10-27 EP disclosed
EP-3721292-A1 ADHESIVE-FREE PHOTOPOLYMER LAYER STRUCTURE Covestro Deutschland AG (DE) 2020-10-14 EP disclosed
EP-3645297-A1 IMPROVED METHOD FOR THE PARTIAL COLOURING OF PLASTIC PARTS Covestro Deutschland AG (DE) 2020-05-06 EP disclosed
EP-3038747-B1 TRANSESTERIFICATION OF AROMATIC ALCOHOLS USING A HETEROGENEOUS CATALYST SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-04-08 EP disclosed
EP-3630875-A1 FILMS HAVING A SCRATCH-RESISTANT COATING AS A COVER LAYER AND LAYERED COMPOSITES COMPRISING SUCH FILMS Covestro Deutschland AG (DE) 2020-04-08 EP disclosed
EP-3383835-B1 A METHOD FOR RECOVERING AN AROMATIC ALCOHOL FROM A MELT POLYMERIZATION, AND A SYSTEM FOR RECOVERING THE SAME SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-07-24 EP disclosed
US-10131178-B2 Layered structure and films for ID documents having improved properties for laser engraving COVESTRO DEUTSCHLAND AG (DE) 2018-11-20 US disclosed
EP-2711353-B1 Process for the continuous manufacture of aryl alkyl carbonate and diaryl carbonate using vapor recompression SABIC GLOBAL TECHNOLOGIES BV (NL) 2018-10-31 EP disclosed
CN-101607908-A Process for preparing diaryl carbonates from dialkyl carbonates BAYER MATERIALSCIENCE AG (DE) 2009-12-23 CN disclosed
CN-100549062-C Inhibiting catalytically active impurities in polycarbonate prepared by melt transesterification process BAYER MATERIALSCIENCE AG (DE) 2009-10-14 CN disclosed
CN-101423473-A Method for producing diaryl carbonates and/or alkylaryl carbonates from dialkyl carbonates BAYER MATERIALSCIENCE AG (DE) 2009-05-06 CN disclosed
US-20090076293-A1 PROCESSES FOR PREPARING DIARYL AND/OR ALKYLARYL CARBONATES FROM DIALKYL CARBONATES BAYER MATERIALSCIENCE AG (DE) 2009-03-19 US disclosed
US-20080319156-A1 Process For The Preparation Of Polycarbonate By The Melt Transesterification Process BAYER MATERIALSCIENCE AG (DE) 2008-12-25 US disclosed
US-20080293960-A1 Process For The Preparation Of Diaryl Carbonates Or Arylalkyl Carbonates From Dialkyl Carbonates BAYER MATERIALSCIENCE AG (DE) 2008-11-27 US disclosed
US-7250483-B2 Inhibition of catalytically active impurities in polycarbonate by the melt transesterification process BAYER MATERIALSCIENCE AG (DE) 2007-07-31 US disclosed
CN-1972983-A Method for producing polycarbonate BAYER MATERIALSCIENCE AG (DE) 2007-05-30 CN disclosed
US-20060004178-A1 Inhibition of catalytically active impurities in polycarbonate by the melt transesterification process COVESTRO DEUTSCHLAND AG (DE) 2006-01-05 US disclosed
CN-1715306-A Inhibiting catalytically active impurities in polycarbonate prepared by melt transesterification process BAYER MATERIALSCIENCE AG (DE) 2006-01-04 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080293960-A1 Process For The Preparation Of Diaryl Carbonates Or Arylalkyl Carbonates From Dialkyl Carbonates HDHD5, ALKBH3, AHR MCL1 2846/4885ACMSD 15/4885PPARG 1983/4885
US-20090076293-A1 PROCESSES FOR PREPARING DIARYL AND/OR ALKYLARYL CARBONATES FROM DIALKYL CARBONATES DHCR7, ADH1C, AKR1C4 MCL1 4416/4885ACMSD 114/4885PPARG 2694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.