Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18605021 | 0.88 | GAA (0.40) | ALDH1A1KLKB1KDM4EGAAMAPT | |
| SCHEMBL30415347 | 0.88 | GAA (0.40) | ALDH1A1KLKB1KDM4EGAAMAPT | |
| SCHEMBL18623280 | 0.86 | KLKB1 (0.33) | KLKB1 | |
| SCHEMBL31067477 | 0.84 | KLKB1 (0.45) | KLKB1 | |
| SCHEMBL18604759 | 0.84 | KLKB1 (0.45) | KLKB1 | |
| SCHEMBL18623250 | 0.81 | F10 (0.40) | ALDH1A1KLKB1KDM4EGAATSHR | |
| SCHEMBL17064405 | 0.78 | KLKB1 (0.52) | ALDH1A1KLKB1KDM4EGAASMN1; SMN2 | |
| SCHEMBL18604730 | 0.76 | KDM4E (0.37) | ALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL3743397 | 0.73 | PDPK1 (0.37) | ALDH1A1KDM4EPOLB | |
| SCHEMBL18623251 | 0.73 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307772-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-113307772-A | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2021-08-27 | — | — | CN | disclosed |
| CN-106257976-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2021-02-02 | — | — | CN | disclosed |