Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 13/20 | 0.45 |
| ▸ | GRN | P28799 | 1/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 5/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18604759 | 1.00 | KLKB1 (0.45) | KLKB1GRNSORT1F10F2 | |
| SCHEMBL18623250 | 0.88 | F10 (0.40) | KLKB1GRNSORT1F10F2 | |
| SCHEMBL28545917 | 0.84 | ALDH1A1 (0.40) | KLKB1 | |
| SCHEMBL18604730 | 0.83 | KDM4E (0.37) | — | |
| SCHEMBL31067421 | 0.82 | KLKB1 (0.47) | KLKB1GRNSORT1F10F2 | |
| SCHEMBL18604643 | 0.82 | KLKB1 (0.47) | KLKB1GRNSORT1F10F2 | |
| SCHEMBL18623280 | 0.80 | KLKB1 (0.33) | KLKB1 | |
| SCHEMBL17064726 | 0.78 | KLKB1 (0.55) | KLKB1GRNSORT1F10F2 | |
| SCHEMBL30415347 | 0.77 | GAA (0.40) | KLKB1 | |
| SCHEMBL18605021 | 0.77 | GAA (0.40) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307772-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2024-06-28 | — | — | CN | disclosed |