Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.44 |
| ▸ | PDE4A | P27815 | 3/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | CREB1 | P16220 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29721178 | 1.00 | CNR1 (0.45) | CNR1CNR2GPR55PDE4BPDE4A | |
| SCHEMBL29274196 | 0.86 | ALDH1A1 (0.40) | CNR1CNR2GPR55PDE4BPDE4A | |
| SCHEMBL28035916 | 0.80 | GAA (0.42) | CNR1CNR2GPR55PDE4BPDE4A | |
| SCHEMBL10455954 | 0.80 | ALDH1A1 (0.36) | CNR1CNR2GPR55PDE4BPDE4A | |
| SCHEMBL2494994 | 0.80 | ALDH1A1 (0.36) | CNR1CNR2GPR55PDE4BPDE4A | |
| SCHEMBL31392539 | 0.79 | HPGD (0.50) | CNR1CNR2GPR55PDE4BPDE4A | |
| SCHEMBL27506599 | 0.79 | HPGD (0.50) | CNR1CNR2GPR55PDE4BPDE4A | |
| Propane SCHEMBL28700749 | 0.77 | BACE1 (0.46) | CNR1CNR2GPR55PDE4BPDE4A | |
| SCHEMBL27496216 | 0.77 | HPGD (0.52) | CNR1CNR2GPR55PDE4BPDE4A | |
| SCHEMBL29721081 | 0.76 | ALDH1A1 (0.41) | CNR1CNR2GPR55GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112672993-B | Novel AUTOTAC chimeric compounds and compositions comprising same for preventing, ameliorating or treating diseases by targeted protein degradation | 奧土择破利悟株式会社 | 2024-03-08 | — | — | CN | disclosed |
| CN-114641282-A | P62 ligand compound and ER-autophagy promoting use thereof | 普罗泰克株式会社 | 2022-06-17 | — | — | CN | disclosed |
| CN-112672993-A | Novel AUTOTAC chimeric compounds and compositions comprising the same for preventing, ameliorating or treating diseases through targeted protein degradation | 普罗泰克株式会社 | 2021-04-16 | — | — | CN | disclosed |