SCHEMBL28035916

SCHEMBL28035916

CCOc1c(-c2ccccc2)ccc(O)c1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.42
LMNA P02545 2/20 0.42
MAPK10 P53779 1/20 0.42
CNR1 P21554 1/20 0.42
CNR2 P34972 1/20 0.42
GPR55 Q9Y2T6 1/20 0.42
SCN5A Q14524 1/20 0.41
CREB1 P16220 1/20 0.40
ESR2 Q92731 1/20 0.40
BACE1 P56817 1/20 0.39
ALDH1A1 P00352 4/20 0.39
HPGD P15428 3/20 0.39
KDM4E B2RXH2 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
HSD17B10 Q99714 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27824476 0.83 ALDH1A1 (0.38) GAALMNAMAPK10CNR1CNR2
SCHEMBL27496216 0.80 HPGD (0.52) GAALMNAMAPK10CNR1CNR2
SCHEMBL28545933 0.80 CNR1 (0.45) GAALMNAMAPK10CNR1CNR2
SCHEMBL29721178 0.80 CNR1 (0.45) GAALMNAMAPK10CNR1CNR2
SCHEMBL31392539 0.79 HPGD (0.50) GAALMNAMAPK10CNR1CNR2
SCHEMBL27506599 0.79 HPGD (0.50) GAALMNAMAPK10CNR1CNR2
SCHEMBL28036440 0.78 MAPT (0.52) LMNACNR1GPR55ESR2BACE1
SCHEMBL18152141 0.78 SCN5A (0.46) GAASCN5AESR2ALDH1A1HPGD
SCHEMBL13828076 0.76 ALDH1A1 (0.46) LMNAALDH1A1HPGDKDM4ETDP1
SCHEMBL29274196 0.75 ALDH1A1 (0.40) GAALMNAMAPK10CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105102422-A Method for producing isocyanate ASAHI KASEI CHEMICALS CORP 2015-11-25 CN disclosed