Valine

Valine

SCHEMBL28546102

CC(C)C(N)C(=O)O.CC(O)CC(=O)NC(C)C(=O)O

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.52
FAAH O00519 4/20 0.39
SMN1; SMN2 Q16637 3/20 0.37
ALDH1A1 P00352 3/20 0.36
MAPT P10636 1/20 0.36
KDM4E B2RXH2 2/20 0.35
MME P08473 2/20 0.34
ACE P12821 1/20 0.34
CPA1 P15085 1/20 0.34
ACE2 Q9BYF1 1/20 0.34
TSHR P16473 1/20 0.34
SLC6A5 Q9Y345 1/20 0.34
DPP4 P27487 1/20 0.33
FAP Q12884 1/20 0.33
DPP8 Q6V1X1 1/20 0.33
DPP9 Q86TI2 1/20 0.33
DPP7 Q9UHL4 1/20 0.33
LTA4H P09960 2/20 0.33
ANPEP P15144 1/20 0.33
ECE1 P42892 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1644161 0.87 FAAH (0.46) FAAHSMN1; SMN2ALDH1A1MAPTKDM4E
SCHEMBL1644160 0.87 FAAH (0.46) FAAHSMN1; SMN2ALDH1A1MAPTKDM4E
Isoleucine SCHEMBL28534804 0.85 MME (0.45) SLC7A5FAAHSMN1; SMN2ALDH1A1MAPT
Glycine SCHEMBL28537104 0.82 FAAH (0.41) FAAHSMN1; SMN2ALDH1A1MAPTKDM4E
D-Glutamate SCHEMBL28535135 0.78 CYP1A2 (0.55) FAAHDPP4DPP8DPP9
SCHEMBL8912805 0.77 SMN1; SMN2 (0.43) SLC7A5FAAHSMN1; SMN2ALDH1A1MAPT
SCHEMBL21261787 0.76 MME (0.41) MMEACECPA1ACE2LTA4H
Valine SCHEMBL9444095 0.76 SLC7A5 (0.62) SLC7A5SMN1; SMN2ALDH1A1MAPTKDM4E
SCHEMBL21341683 0.76 SLC7A5 (0.50) SLC7A5FAAHSMN1; SMN2ALDH1A1MAPT
Valine SCHEMBL9444094 0.76 SLC7A5 (0.62) SLC7A5SMN1; SMN2ALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108017555-B Beta-hydroxybutyryl-amino acid compound and preparation method and application thereof 郑州海斯威生物技术有限公司 2021-03-26 CN disclosed