Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 4/20 | 0.54 |
| ▸ | ACE | P12821 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | XIAP | P98170 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PEPD | P12955 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28546112 | 1.00 | REN (0.54) | RENACEKMT2AL3MBTL1XIAP | |
| SCHEMBL30051407 | 0.87 | KMT2A (0.52) | RENACEKMT2AL3MBTL1XIAP | |
| SCHEMBL15251740 | 0.83 | KMT2A (0.59) | ACEKMT2AL3MBTL1LMNALTA4H | |
| SCHEMBL15251739 | 0.83 | KMT2A (0.59) | ACEKMT2AL3MBTL1LMNALTA4H | |
| SCHEMBL18018530 | 0.83 | KMT2A (0.53) | RENACEKMT2AL3MBTL1XIAP | |
| SCHEMBL23260256 | 0.82 | XIAP (0.55) | RENACEKMT2AL3MBTL1XIAP | |
| SCHEMBL31202564 | 0.82 | XIAP (0.55) | RENACEKMT2AL3MBTL1XIAP | |
| SCHEMBL29615598 | 0.82 | XIAP (0.55) | RENACEKMT2AL3MBTL1XIAP | |
| SCHEMBL31202557 | 0.82 | XIAP (0.55) | RENACEKMT2AL3MBTL1XIAP | |
| SCHEMBL21246820 | 0.81 | XIAP (0.63) | RENACEKMT2AL3MBTL1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108017555-B | Beta-hydroxybutyryl-amino acid compound and preparation method and application thereof | 郑州海斯威生物技术有限公司 | 2021-03-26 | — | — | CN | disclosed |