Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | AKT1 | P31749 | 10/20 | 0.51 |
| ▸ | GAB1 | Q13480 | 3/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | AKT2 | P31751 | 1/20 | 0.51 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.51 |
| ▸ | IRS1 | P35568 | 1/20 | 0.51 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.50 |
| ▸ | GHSR | Q92847 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26965400 | 0.81 | CA2 (0.64) | CA2CA12CA1CA9SMN1; SMN2 | |
| SCHEMBL14341518 | 0.81 | GAA (0.51) | CA2CA12CA1CA9SMN1; SMN2 | |
| SCHEMBL14341521 | 0.81 | GAA (0.51) | CA2CA12CA1CA9SMN1; SMN2 | |
| SCHEMBL11557623 | 0.80 | CA1 (0.58) | CA2CA12CA1CA9SMN1; SMN2 | |
| SCHEMBL28414948 | 0.80 | CA2 (0.67) | CA2CA12CA1CA9SMN1; SMN2 | |
| SCHEMBL10926573 | 0.80 | CA2 (0.62) | CA2CA12CA1CA9SMN1; SMN2 | |
| SCHEMBL8671802 | 0.79 | CA12 (0.67) | CA2CA12CA1CA9GHSR | |
| SCHEMBL13254478 | 0.79 | EPHX1 (0.49) | CA2CA12CA1CA9SMN1; SMN2 | |
| SCHEMBL38662674 | 0.78 | LMNA (0.74) | CA2SMN1; SMN2LMNAHTTAKT1 | |
| SCHEMBL38662567 | 0.78 | LMNA (0.74) | CA2SMN1; SMN2LMNAHTTAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112472822-B | Construction and application of endoplasmic reticulum targeted nano drug delivery system | 浙江大学 | 2022-05-27 | — | — | CN | claimed |
| CN-112472822-B | Construction and application of endoplasmic reticulum targeted nano drug delivery system | 浙江大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-112472822-A | Construction and application of endoplasmic reticulum targeted nano drug delivery system | 浙江大学 | 2021-03-12 | — | — | CN | disclosed |