Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.63 |
| ▸ | ACHE | P22303 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 2/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30443457 | 1.00 | SIGMAR1 (0.63) | SIGMAR1ACHEKDM4EALDH1A1MAPT | |
| SCHEMBL28801570 | 0.86 | SIGMAR1 (0.70) | SIGMAR1ACHEKDM4EALDH1A1MAPT | |
| SCHEMBL27461651 | 0.83 | SIGMAR1 (0.59) | SIGMAR1ACHEKDM4EALDH1A1MAPT | |
| SCHEMBL12013920 | 0.83 | SIGMAR1 (0.70) | SIGMAR1ACHEKDM4EALDH1A1MAPT | |
| SCHEMBL493570 | 0.83 | SIGMAR1 (0.58) | SIGMAR1ACHEOPRM1CHRM2CHRM3 | |
| SCHEMBL20804357 | 0.82 | SIGMAR1 (0.90) | SIGMAR1KDM4EALDH1A1MAPTGAA | |
| SCHEMBL28186295 | 0.82 | SIGMAR1 (0.90) | SIGMAR1KDM4EALDH1A1MAPTGAA | |
| SCHEMBL6943757 | 0.82 | SIGMAR1 (0.68) | SIGMAR1ACHEKDM4EALDH1A1MAPT | |
| SCHEMBL22829113 | 0.82 | SIGMAR1 (0.68) | SIGMAR1ACHEKDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL11535920 | 0.81 | SIGMAR1 (0.67) | SIGMAR1ACHEKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111925357-B | Acylhydrazone compound, pharmaceutical composition and application thereof | 中国科学院昆明植物研究所 | 2023-06-06 | — | — | CN | disclosed |
| CN-111925357-A | Acylhydrazone compound, pharmaceutical composition and application thereof | 中国科学院昆明植物研究所 | 2020-11-13 | — | — | CN | disclosed |