Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | EED | O75530 | 1/20 | 0.34 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29200248 | 0.99 | PTPN11 (0.39) | PTPN11KMT2ABRD4L3MBTL1KDM4E | |
| Boric Acid SCHEMBL28547119 | 0.82 | PTPN11 (0.41) | PTPN11BRD4L3MBTL1KDM4EUBE2N | |
| SCHEMBL9967579 | 0.81 | PTPN11 (0.42) | PTPN11BRD4L3MBTL1KDM4EUBE2N | |
| SCHEMBL16884156 | 0.78 | PTPN11 (0.41) | PTPN11BRD4L3MBTL1KDM4EUBE2N | |
| SCHEMBL29604791 | 0.78 | CA1 (0.46) | PTPN11BRD4L3MBTL1KDM4EUBE2N | |
| SCHEMBL14685251 | 0.78 | CA1 (0.46) | PTPN11BRD4L3MBTL1KDM4EUBE2N | |
| SCHEMBL20846089 | 0.78 | BRD4 (0.51) | PTPN11KMT2ABRD4L3MBTL1KDM4E | |
| Potassium Ion SCHEMBL20548099 | 0.78 | PTPN11 (0.39) | PTPN11BRD4L3MBTL1KDM4EUBE2N | |
| SCHEMBL31554424 | 0.78 | HTR6 (0.38) | PTPN11KMT2ABRD4EEDSLC22A12 | |
| SCHEMBL18682865 | 0.76 | PTPN11 (0.39) | PTPN11KMT2ABRD4L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110637022-B | Pyrrolopyrimidine derivatives as inhibitors of influenza virus replication | 共晶制药公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-112638477-A | Pyrrolo [2,3-B ] pyridine derivatives as inhibitors of influenza virus replication | 共晶制药公司 | 2021-04-09 | — | — | CN | disclosed |
| CN-110637022-A | Pyrrolopyrimidine derivatives as inhibitors of influenza virus replication | 共晶制药公司 | 2019-12-31 | — | — | CN | disclosed |