Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.69 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | WRN | Q14191 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19493077 | 1.00 | MGLL (0.69) | MGLLFAAHALDH1A1HPGDCYP1A2 | |
| SCHEMBL10067465 | 0.89 | MGLL (0.55) | MGLLFAAHALDH1A1HPGDCYP1A2 | |
| SCHEMBL9736882 | 0.83 | MGLL (0.65) | MGLLFAAHALDH1A1HPGDCYP1A2 | |
| SCHEMBL15483488 | 0.83 | MGLL (1.00) | MGLLFAAHALDH1A1HPGDBLM | |
| SCHEMBL15082420 | 0.83 | MGLL (1.00) | MGLLFAAHALDH1A1HPGDBLM | |
| SCHEMBL30009171 | 0.83 | MGLL (1.00) | MGLLFAAHALDH1A1HPGDBLM | |
| SCHEMBL140275 | 0.83 | MGLL (1.00) | MGLLFAAHALDH1A1HPGDBLM | |
| SCHEMBL9643398 | 0.83 | MGLL (1.00) | MGLLFAAHALDH1A1HPGDBLM | |
| SCHEMBL349749 | 0.83 | MGLL (1.00) | MGLLFAAHALDH1A1HPGDBLM | |
| SCHEMBL24164310 | 0.83 | MGLL (0.69) | MGLLFAAHALDH1A1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114917361-A | Antibody Drug Conjugates (ADC) and antibody prodrug conjugates (APDC) with enzyme cleavable groups | 拜耳医药股份有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-107635586-B | Antibody-drug conjugates (ADC) of KSP inhibitors with aglycosylated anti-TWEAKR antibodies | 拜耳医药股份有限公司 | 2021-09-24 | — | — | CN | disclosed |
| CN-106163568-B | Antibody Drug Conjugates (ADC) containing spindle Kinesin (KSP) | 拜耳制药股份公司 | 2021-03-23 | — | — | CN | disclosed |