Sugi Predict

Sugi Predict / Compounds / SCHEMBL140275

SCHEMBL140275

SCHEMBL140275

O=C1C=CC(=O)N1CCOCCOCCOCCN1C(=O)C=CC1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MGLL Q99685 9/20 1.00
▸ FAAH O00519 5/20 0.56
▸ ALDH1A1 P00352 2/20 0.54
▸ LMNA P02545 2/20 0.54
▸ MAPT P10636 2/20 0.54
▸ NPSR1 Q6W5P4 2/20 0.54
▸ HSP90AA1 P07900 1/20 0.54
▸ TLR9 Q9NR96 1/20 0.54
▸ TP53 P04637 1/20 0.54
▸ PKM P14618 1/20 0.54
▸ HPGD P15428 1/20 0.54
▸ XBP1 P17861 1/20 0.54
▸ MAPK1 P28482 1/20 0.54
▸ HTT P42858 1/20 0.54
▸ RECQL P46063 1/20 0.54
▸ RAB9A P51151 1/20 0.54
▸ SMN1; SMN2 Q16637 1/20 0.54
▸ GPR35 Q9HC97 1/20 0.54
▸ GPR55 Q9Y2T6 1/20 0.54
▸ PTGS1 P23219 7/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30009171 1.00 MGLL (1.00) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL15483488 1.00 MGLL (1.00) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL9643398 1.00 MGLL (1.00) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL349749 1.00 MGLL (1.00) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL15082420 1.00 MGLL (1.00) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL407969 0.97 MGLL (0.95) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL16625603 0.91 MGLL (0.83) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL19708788 0.91 MGLL (0.83) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL24797580 0.89 MGLL (0.80) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL21014255 0.89 MGLL (0.80) MGLLFAAHALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 958 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4623081-A2 SPLIT SYNTHESIS OF LONG RNAS Prime Medicine, Inc. (US) 2025-10-01 — — EP claimed
US-20250295745-A1 CROSS-LINKED TUMOR LYSATE SPHERICAL NUCLEIC ACIDS AS CANCER VACCINES NORTHWESTERN UNIVERSITY 2025-09-25 — — US claimed
EP-4541374-A2 DEFINED MULTI-CONJUGATE OLIGONUCLEOTIDES Mpeg LA, L.l.c. (US) 2025-04-23 — — EP claimed
US-20240191240-A1 DEFINED MULTI-CONJUGATES OLIGONUCLEOTIDES MPEG LA L L C (US) 2024-06-13 — — US claimed
CN-116262820-B Preparation method and application of reversibly crosslinked furan dicarboxylic acid polyester 浙江恒逸石化研究院有限公司 2024-06-07 — — CN claimed
CN-114252592-B Soluble fms-like tyrosine kinase-1 detection kit and preparation method and application thereof 广州万孚生物技术股份有限公司 2024-05-31 — — CN claimed
WO-2024112876-A2 SPLIT SYNTHESIS OF LONG RNAS PRIME MEDICINE, INC. (US) 2024-05-30 — — WO claimed
CN-113717455-B Resin composition, thermoplastic resin composite material, and thermoplastic resin article 中国石油化工股份有限公司 2023-12-29 — — CN claimed
WO-2023220678-A1 CROSS-LINKED TUMOR LYSATE SPHERICAL NUCLEIC ACIDS AS CANCER VACCINES NORTHWESTERN UNIVERSITY (US) 2023-11-16 — — WO claimed
US-11767531-B2 Defined multi-conjugates oligonucleotides MPEG LA, LLC (US) 2023-09-26 — — US claimed
CN-116425993-A Preparation method of hyperbranched polycarboxylate dispersant 上海交通大学 2023-07-14 — — CN claimed
US-20220290148-A1 DEFINED MULTI-CONJUGATES OLIGONUCLEOTIDES MPEG LA L L C (US) 2022-09-15 — — US claimed
US-11332880-B2 Modifying natural feathers for use in sporting goods DURABIRD (US) 2022-05-17 — — US claimed
CN-108026527-B Defined multiconjugated oligonucleotides MPEG LA有限责任公司 2022-05-10 — — CN claimed
CN-113717455-A Resin composition, thermoplastic resin composite material, and thermoplastic resin article 中国石油化工股份有限公司 2021-11-30 — — CN claimed
CN-110790958-B Thermally reversible crosslinked rubber and preparation method thereof 北京化工大学 2021-02-05 — — CN claimed
CN-110790958-A Thermally reversible crosslinked rubber and preparation method thereof 北京化工大学 2020-02-14 — — CN claimed
US-20260147001-A1 PROTEIN SEQUENCING VIA COUPLING OF POLYMERIZABLE MOLECULES GLYPHIC BIOTECHNOLOGIES, INC. (US) 2026-05-28 — — US disclosed
US-20070072199-A1 Covalent methods for immobilization of thiolated biomolecules on siliceous and metallic surfaces THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2007-03-29 — — US disclosed
WO-2004113872-A2 COVALENT METHODS FOR IMMOBILIZATION OF THIOLATED BIOMOLECULES ON SILICEOUS AND METALLIC SURFACES THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2004-12-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11767531-B2 Defined multi-conjugates oligonucleotides BOD1L1, AGO2, AS3MT MGLL 3895/4885FAAH 4777/4885ALDH1A1 1771/4885
US-20220290148-A1 DEFINED MULTI-CONJUGATES OLIGONUCLEOTIDES TLR9, L3MBTL3, L3MBTL1 MGLL 3848/4885FAAH 4777/4885ALDH1A1 2416/4885
US-20240191240-A1 DEFINED MULTI-CONJUGATES OLIGONUCLEOTIDES TLR9, TELO2, NSUN3 MGLL 3903/4885FAAH 4804/4885ALDH1A1 2205/4885
US-20260147001-A1 PROTEIN SEQUENCING VIA COUPLING OF POLYMERIZABLE MOLECULES SPPL2A, SPPL2B, PTMS MGLL 3610/4885FAAH 4627/4885ALDH1A1 4782/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.