Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MMP2 | P08253 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28552201 | 0.92 | MMP2 (0.49) | MAPTMMP2NPSR1ALDH1A1ACHE | |
| SCHEMBL28547430 | 0.83 | MMP2 (0.51) | MAPTMMP2SMN1; SMN2ALDH1A1ACHE | |
| SCHEMBL28541517 | 0.79 | MMP2 (0.47) | MMP2SMN1; SMN2ALDH1A1ACHEHTT | |
| SCHEMBL28542268 | 0.78 | MAPT (0.47) | MAPTSMN1; SMN2ALDH1A1ACHEHTT | |
| SCHEMBL29620267 | 0.77 | MMP2 (0.47) | MMP2NPSR1SMN1; SMN2ALDH1A1ACHE | |
| SCHEMBL6981036 | 0.74 | MMP2 (0.54) | MAPTMMP2NPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28532121 | 0.74 | NPSR1 (0.51) | MAPTMMP2NPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28534735 | 0.73 | MAPT (0.40) | MAPTMMP2NPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28550859 | 0.71 | MMP2 (0.51) | MAPTMMP2SMN1; SMN2ALDH1A1ACHE | |
| SCHEMBL1792783 | 0.70 | MAPT (0.58) | MAPTMMP2NPSR1ALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112608269-B | Method for catalytically synthesizing pyrrolidine by weak interaction of chalcogen | 山东大学 | 2022-05-06 | — | — | CN | disclosed |
| CN-112608269-A | Method for catalytically synthesizing pyrrolidine by weak interaction of chalcogen | 山东大学 | 2021-04-06 | — | — | CN | disclosed |