Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11973569 | 0.87 | MMP2 (0.59) | MMP2MAPTACHENPSR1ALDH1A1 | |
| SCHEMBL6981947 | 0.87 | MMP2 (0.59) | MMP2MAPTACHENPSR1ALDH1A1 | |
| SCHEMBL17643989 | 0.80 | MMP2 (0.53) | MMP2MAPTACHEMEN1KMT2A | |
| SCHEMBL19384141 | 0.80 | MMP2 (0.53) | MMP2MAPTACHEMEN1KMT2A | |
| SCHEMBL6977795 | 0.80 | LMNA (0.63) | MMP2MAPTNPSR1KMT2AALDH1A1 | |
| SCHEMBL6977791 | 0.80 | LMNA (0.63) | MMP2MAPTNPSR1KMT2AALDH1A1 | |
| SCHEMBL6977799 | 0.80 | LMNA (0.63) | MMP2MAPTNPSR1KMT2AALDH1A1 | |
| SCHEMBL6081659 | 0.77 | MMP2 (0.55) | MMP2MAPTACHENPSR1ALDH1A1 | |
| SCHEMBL8471111 | 0.77 | MMP2 (0.55) | MMP2MAPTACHENPSR1ALDH1A1 | |
| SCHEMBL2600493 | 0.77 | MMP2 (0.55) | MMP2MAPTACHENPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724569-B1 | PROCESS FOR THE PREPARATION OF AN OXIRANE, AZIRIDINE OR CYCLOPROPANE | AVECIA LTD (GB) | 2003-03-12 | — | — | EP | disclosed |
| US-5703246-A | REACTING AN ORGANOMETALLIC COMPOUND WITH ORGANOSULFUR COMPOUND | ZENECA LIMITED (GB) | 1997-12-30 | — | — | US | disclosed |