Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | TPH1 | P17752 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | GRB2 | P62993 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28547644 | 1.00 | SLC1A3 (0.40) | SLC1A3SLC1A2SLC1A1MMP2SLC7A5 | |
| SCHEMBL30444607 | 0.80 | PTPN1 (0.39) | SLC1A3SLC1A2SLC1A1SLC7A5PTGS1 | |
| Iodofalan SCHEMBL44619 | 0.74 | SLC7A5 (0.69) | SLC7A5PTGS1ALPIPKMXIAP | |
| Iodofalan SCHEMBL44618 | 0.74 | SLC7A5 (0.69) | SLC7A5PTGS1ALPIPKMXIAP | |
| Iodofalan SCHEMBL44620 | 0.74 | SLC7A5 (0.69) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL1819865 | 0.73 | SLC1A1 (0.73) | SLC1A3SLC1A2SLC1A1SLC7A5PTGS1 | |
| SCHEMBL9818606 | 0.73 | SLC1A1 (0.46) | SLC1A3SLC1A2SLC1A1SLC7A5 | |
| SCHEMBL1818259 | 0.73 | SLC1A1 (0.73) | SLC1A3SLC1A2SLC1A1SLC7A5PTGS1 | |
| SCHEMBL1819970 | 0.73 | SLC1A1 (0.73) | SLC1A3SLC1A2SLC1A1SLC7A5PTGS1 | |
| Iodofalan SCHEMBL23824892 | 0.72 | SLC7A5 (0.67) | SLC7A5PTGS1ALPIPKMXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109593052-B | Radioactive arginine derivatives for diagnosis and treatment and preparation method thereof | 首都医科大学 | 2021-04-20 | — | — | CN | disclosed |