Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 8/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 7/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 7/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 6/20 | 0.40 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.35 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9818565 | 0.87 | SLC1A1 (0.49) | SLC1A1SLC1A2SLC1A3SLC7A5GRIK1 | |
| SCHEMBL10783477 | 0.81 | SLC7A5 (0.41) | SLC1A1SLC1A2SLC1A3SLC7A5GRIK1 | |
| SCHEMBL28729833 | 0.79 | SLC7A5 (0.48) | SLC1A1SLC1A2SLC1A3SLC7A5GRIK1 | |
| SCHEMBL9800490 | 0.79 | SLC7A5 (0.48) | SLC1A1SLC1A2SLC1A3SLC7A5GRIK1 | |
| SCHEMBL4586895 | 0.79 | SLC7A5 (0.48) | SLC1A1SLC1A2SLC1A3SLC7A5GRIK1 | |
| SCHEMBL10667207 | 0.79 | SLC7A5 (0.48) | SLC1A1SLC1A2SLC1A3SLC7A5GRIK1 | |
| SCHEMBL1504409 | 0.79 | SLC7A5 (0.48) | SLC1A1SLC1A2SLC1A3SLC7A5GRIK1 | |
| SCHEMBL27644228 | 0.79 | SLC7A5 (0.42) | SLC1A1SLC1A2SLC1A3SLC7A5GRIK1 | |
| SCHEMBL27644223 | 0.79 | SLC7A5 (0.42) | SLC1A1SLC1A2SLC1A3SLC7A5GRIK1 | |
| SCHEMBL1527344 | 0.78 | GFPT1 (0.46) | SLC1A1SLC1A2SLC1A3SLC7A5GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028627-A | Controlling blood pressure during chemotherapy | CORNELL RESEARCH FOUNDATION, INC. (US) | 1991-07-02 | — | — | US | disclosed |