Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 8/20 | 0.55 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.55 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.55 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.55 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.55 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | FABP3 | P05413 | 5/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL340006 | 1.00 | LPAR1 (0.55) | LPAR1ENPP2LPAR3LPAR2LPAR4 | |
| SCHEMBL21957629 | 0.96 | LPAR1 (0.55) | LPAR1ENPP2LPAR3LPAR2LPAR4 | |
| SCHEMBL3888681 | 0.91 | FABP3 (0.59) | LPAR1ENPP2LPAR3LPAR2LPAR4 | |
| SCHEMBL22802111 | 0.91 | FABP3 (0.59) | LPAR1ENPP2LPAR3LPAR2LPAR4 | |
| SCHEMBL20484292 | 0.91 | FABP3 (0.59) | LPAR1ENPP2LPAR3LPAR2LPAR4 | |
| SCHEMBL11576044 | 0.91 | ENPP2 (0.49) | LPAR1ENPP2LPAR3LPAR2LPAR4 | |
| SCHEMBL503670 | 0.91 | ENPP2 (0.49) | LPAR1ENPP2LPAR3LPAR2LPAR4 | |
| SCHEMBL504260 | 0.91 | ENPP2 (0.49) | LPAR1ENPP2LPAR3LPAR2LPAR4 | |
| SCHEMBL2938334 | 0.90 | P2RY10 (0.58) | LPAR1ENPP2LPAR3LPAR2LPAR4 | |
| SCHEMBL27652705 | 0.90 | LPAR1 (0.59) | LPAR1ENPP2LPAR3LPAR2LPAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384199-A | Method and formulation for improving skin permeation lag time of roflumilast | 阿尔库缇斯股份有限公司 | 2021-02-19 | — | — | CN | disclosed |