Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 6/20 | 0.49 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.49 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.49 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.49 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.49 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.49 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.49 |
| ▸ | DGKA | P23743 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PAM | P19021 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11576044 | 1.00 | ENPP2 (0.49) | ENPP2LPAR3LPAR1LPAR6LPAR4 | |
| SCHEMBL503670 | 1.00 | ENPP2 (0.49) | ENPP2LPAR3LPAR1LPAR6LPAR4 | |
| SCHEMBL27719763 | 0.98 | ENPP2 (0.46) | ENPP2LPAR3LPAR1LPAR6LPAR4 | |
| SCHEMBL340006 | 0.91 | LPAR1 (0.55) | ENPP2LPAR3LPAR1LPAR6LPAR4 | |
| SCHEMBL10703309 | 0.89 | DGKA (0.55) | ENPP2LPAR3LPAR1LPAR6LPAR4 | |
| SCHEMBL3924198 | 0.89 | DGKA (0.55) | ENPP2LPAR3LPAR1LPAR6LPAR4 | |
| SCHEMBL18409606 | 0.89 | DGKA (0.55) | ENPP2LPAR3LPAR1LPAR6LPAR4 | |
| SCHEMBL5146983 | 0.89 | DGKA (0.55) | ENPP2LPAR3LPAR1LPAR6LPAR4 | |
| SCHEMBL3422445 | 0.89 | DGKA (0.55) | ENPP2LPAR3LPAR1LPAR6LPAR4 | |
| SCHEMBL28048302 | 0.89 | DGKA (0.55) | ENPP2LPAR3LPAR1LPAR6LPAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120028033-A1 | PHASE-SEPARATED STRUCTURE AND PRODUCTION METHOD THEREFOR | TOHOKU UNIVERSITY (JP) | 2012-02-02 | — | — | US | disclosed |