Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | PHGDH | O43175 | 2/20 | 0.44 |
| ▸ | CASR | P41180 | 2/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ACACB | O00763 | 2/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CCR1 | P32246 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857649 | 0.89 | NOTUM (0.51) | NOTUMCASRACACB | |
| SCHEMBL2854450 | 0.84 | CHRM4 (0.46) | NOTUMCASR | |
| SCHEMBL23387213 | 0.79 | NOTUM (0.67) | NOTUMPHGDHCASRPTGDR2LMNA | |
| SCHEMBL23387210 | 0.79 | NOTUM (0.67) | NOTUMPHGDHCASRPTGDR2LMNA | |
| SCHEMBL29689683 | 0.77 | NOTUM (0.57) | NOTUMPHGDHCASRPTGDR2LMNA | |
| SCHEMBL22499987 | 0.77 | NOTUM (0.57) | NOTUMPHGDHCASRPTGDR2LMNA | |
| SCHEMBL2854225 | 0.75 | CCR1 (0.60) | CCR1 | |
| SCHEMBL14989237 | 0.74 | MAPK13 (0.44) | LMNAMAPK1 | |
| SCHEMBL2855614 | 0.71 | CCR1 (0.50) | CCR1 | |
| SCHEMBL17269741 | 0.71 | CCR2 (0.62) | SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |