Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | CTH | P32929 | 1/20 | 0.38 |
| ▸ | CBS | P35520 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PTPRB | P23467 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951822 | 0.76 | — | — | |
| SCHEMBL921532 | 0.76 | — | — | |
| SCHEMBL4323705 | 0.76 | TSHR (0.39) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL21409743 | 0.75 | — | — | |
| SCHEMBL4323713 | 0.74 | LDHA (0.40) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL804118 | 0.73 | ALDH1A1 (0.47) | TSHRSMN1; SMN2HSD17B10HPGDALDH1A1 | |
| SCHEMBL3271834 | 0.73 | TSHR (0.53) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL11684398 | 0.72 | LDHA (0.38) | TSHRCTHCBSTHPOTHRB | |
| Acetic Acid SCHEMBL11151335 | 0.71 | FFAR3 (0.47) | TSHRCTHCBSTHPOTHRB | |
| Malonic Acid SCHEMBL10817903 | 0.71 | LDHA (0.60) | TSHREGLN1SMN1; SMN2LDHASRR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112500353-B | Levosimendan prodrug compound, preparation method and application thereof | 北京晨光同创医药研究院有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-112500353-A | Levosimendan prodrug compound, preparation method and application thereof | 北京晨光同创医药研究院有限公司 | 2021-03-16 | — | — | CN | disclosed |