Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.33 |
| ▸ | MAP2K6 | P52564 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.33 |
| ▸ | NEK10 | Q6ZWH5 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | MAOA | P21397 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3662854 | 0.75 | GPR3 (0.54) | GPR3LMNAHTTKMT2ALCK | |
| Benzonaphthyridine SCHEMBL51197 | 0.75 | GPR3 (1.00) | GPR3LMNAHTTKMT2ALCK | |
| Benzonaphthyridine SCHEMBL30897319 | 0.75 | GPR3 (1.00) | GPR3LMNAHTTKMT2ALCK | |
| Benzonaphthyridine SCHEMBL29600756 | 0.75 | GPR3 (1.00) | GPR3LMNAHTTKMT2ALCK | |
| SCHEMBL7052017 | 0.72 | GPR3 (0.64) | GPR3LMNAHTTKMT2ALCK | |
| SCHEMBL4485428 | 0.69 | GPR3 (0.87) | GPR3LMNAHTTKMT2ALCK | |
| SCHEMBL11198396 | 0.64 | GPR3 (0.64) | GPR3LMNAHTTKMT2AKDM4E | |
| Benzonaphthyridine SCHEMBL38660425 | 0.63 | GPR3 (0.70) | GPR3LMNAHTTKMT2ALCK | |
| SCHEMBL28981702 | 0.61 | GPR3 (0.59) | GPR3LMNAHTTKMT2ALCK | |
| SCHEMBL1179339 | 0.61 | GPR3 (0.67) | GPR3LMNAHTTKMT2ALCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115350279-A | anti-HER 2 combinations for the treatment of tumors | 博笛生物科技有限公司 | 2022-11-18 | — | — | CN | disclosed |
| CN-115337402-A | Combination therapeutic compositions and combination therapeutic methods for treating cancer | 博笛生物科技有限公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-115252792-A | anti-EGFR combinations for the treatment of tumors | 博笛生物科技有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-114716555-A | Compounds and compositions for targeting EGFR expressing tumors | 博笛生物科技有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114671954-A | Compounds and compositions targeting HER2 positive tumors | 博笛生物科技有限公司 | 2022-06-28 | — | — | CN | disclosed |
| CN-113633783-A | Compounds and compositions for immunotherapy | 博笛生物科技有限公司 | 2021-11-12 | — | — | CN | disclosed |
| CN-105899539-B | Compounds and compositions for immunotherapy | 博笛生物科技有限公司 | 2021-11-09 | — | — | CN | disclosed |
| CN-112587672-A | anti-PD-L1 conjugates for the treatment of tumors | 博笛生物科技有限公司 | 2021-04-02 | — | — | CN | disclosed |
| CN-112546230-A | Combination therapeutic compositions and combination therapeutic methods for treating cancer | 博笛生物科技有限公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-112546231-A | Combination therapeutic compositions and combination therapeutic methods for treating cancer | 博笛生物科技有限公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-112546238-A | anti-PD-L1 conjugates for the treatment of tumors | 博笛生物科技有限公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-109152832-A | Anti-CD 20 for treating tumour combines | 博笛生物科技有限公司 | 2019-01-04 | — | — | CN | disclosed |