SCHEMBL28548352

SCHEMBL28548352

O=Cc1cc(C=O)c2ccsc2c1

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 5/20 0.48
ERN1 O75460 3/20 0.31
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
THRB P10828 1/20 0.31
BLM P54132 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PTGS1 P23219 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9527033 0.77 CYP2A6 (0.47) CYP2A6ERN1MEN1LMNATHRB
SCHEMBL2263913 0.73 CYP2A6 (0.57) CYP2A6ERN1MEN1LMNATHRB
SCHEMBL30430903 0.71 ICAM1 (0.41) CYP2A6MEN1LMNATHRBBLM
SCHEMBL27687556 0.71 ICAM1 (0.41) CYP2A6MEN1LMNATHRBBLM
SCHEMBL1894396 0.69 CYP2A6 (0.71) CYP2A6TDP1PTGS1ALDH1A1
SCHEMBL4444860 0.68 CYP2A6 (0.44) CYP2A6ERN1MEN1LMNATHRB
SCHEMBL14178256 0.67 CYP2A6 (0.57) CYP2A6ERN1MEN1LMNATHRB
SCHEMBL6980313 0.67 CYP2A6 (0.43) CYP2A6ERN1MEN1LMNATHRB
SCHEMBL6984412 0.67 CYP2A6 (0.47) CYP2A6MEN1LMNATHRBBLM
SCHEMBL31280833 0.67 CYP2A6 (0.43) CYP2A6ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112638895-A Organic compound containing chalcogen element, organic semiconductor material, organic semiconductor film, and organic electric field effect transistor 国立大学法人东京大学 2021-04-09 CN disclosed