Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.67 |
| ▸ | APP | P05067 | 3/20 | 0.59 |
| ▸ | TTR | P02766 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TOP2A | P11388 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28560586 | 0.85 | KDM4E (0.61) | APPTTRPTPN1ALDH1A1MAPT | |
| SCHEMBL7245926 | 0.84 | TOP2A (0.79) | EPHX2APPTTRPTPN1ALDH1A1 | |
| SCHEMBL29681816 | 0.84 | TOP2A (0.79) | EPHX2APPTTRPTPN1ALDH1A1 | |
| SCHEMBL7245921 | 0.84 | TOP2A (0.79) | EPHX2APPTTRPTPN1ALDH1A1 | |
| SCHEMBL7247036 | 0.82 | EPHX2 (0.70) | EPHX2APPTTRPTPN1ALDH1A1 | |
| SCHEMBL7247037 | 0.82 | EPHX2 (0.70) | EPHX2APPTTRPTPN1ALDH1A1 | |
| Methyl Cis-Ferulate SCHEMBL2085720 | 0.81 | EPHX2 (1.00) | EPHX2APPTTRPTPN1ALDH1A1 | |
| Methyl Cis-Ferulate SCHEMBL29406729 | 0.81 | EPHX2 (1.00) | EPHX2APPTTRPTPN1ALDH1A1 | |
| Methyl Cis-Ferulate SCHEMBL510492 | 0.81 | EPHX2 (1.00) | EPHX2APPTTRPTPN1ALDH1A1 | |
| Methyl Cis-Ferulate SCHEMBL30211782 | 0.79 | EPHX2 (0.97) | EPHX2APPTTRPTPN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109678923-B | Tripterine (iso) ferulic acid ester derivative and preparation method and application thereof | 中国药科大学 | 2021-04-27 | — | — | CN | disclosed |