Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.70 |
| ▸ | FDPS | P14324 | 2/20 | 0.65 |
| ▸ | TOP2A | P11388 | 2/20 | 0.63 |
| ▸ | APP | P05067 | 7/20 | 0.62 |
| ▸ | TTR | P02766 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 3/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.58 |
| ▸ | STAT3 | P40763 | 2/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.58 |
| ▸ | RELA | Q04206 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7247037 | 1.00 | EPHX2 (0.70) | EPHX2FDPSTOP2AAPPTTR | |
| SCHEMBL29681816 | 0.89 | TOP2A (0.79) | EPHX2FDPSTOP2AAPPTTR | |
| SCHEMBL7245926 | 0.89 | TOP2A (0.79) | EPHX2FDPSTOP2AAPPTTR | |
| SCHEMBL7245921 | 0.89 | TOP2A (0.79) | EPHX2FDPSTOP2AAPPTTR | |
| SCHEMBL1378809 | 0.87 | APP (0.80) | TOP2AAPPMAOBKDM4ECYP2D6 | |
| SCHEMBL4621755 | 0.86 | KDM4E (0.73) | TOP2AAPPTTRMAOBPTPN1 | |
| SCHEMBL7252136 | 0.86 | KDM4E (0.73) | TOP2AAPPTTRMAOBPTPN1 | |
| SCHEMBL7246649 | 0.85 | FDPS (0.71) | EPHX2FDPSTOP2AKDM4EMAPT | |
| SCHEMBL7246653 | 0.85 | FDPS (0.71) | EPHX2FDPSTOP2AKDM4EMAPT | |
| SCHEMBL14157952 | 0.85 | TOP2A (0.68) | TOP2AAPPMAOBKDM4ECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1124297-C | Photocrosslinkable polymers | ROLIC AG (CH) | 2003-10-15 | — | — | CN | disclosed |
| US-6632909-B2 | Alkylenedi- acrylates and acrylamides containing phenyl groups substituted with at least two alkoxy or fluoroalkoxy groups; use in orientation layers for liquid crystals, and in optical components, in particular hybrid layer elements. | ROLIC AG (CH) | 2003-10-14 | — | — | US | disclosed |
| US-20020061996-A1 | Photocrosslinkable polymers | BUCHECKER RICHARD (CH) | 2002-05-23 | — | — | US | disclosed |
| CN-1194996-A | Photocrosslinkable polymers | ROLIC AG (CH) | 1998-10-07 | — | — | CN | disclosed |