Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.79 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.74 |
| ▸ | MAOB | P27338 | 3/20 | 0.67 |
| ▸ | APP | P05067 | 3/20 | 0.66 |
| ▸ | TTR | P02766 | 2/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | ALPI | P09923 | 2/20 | 0.61 |
| ▸ | ALPG | P10696 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7245926 | 1.00 | TOP2A (0.79) | TOP2AEPHX2MAOBAPPTTR | |
| SCHEMBL7245921 | 1.00 | TOP2A (0.79) | TOP2AEPHX2MAOBAPPTTR | |
| SCHEMBL7247037 | 0.89 | EPHX2 (0.70) | TOP2AEPHX2MAOBAPPTTR | |
| SCHEMBL7247036 | 0.89 | EPHX2 (0.70) | TOP2AEPHX2MAOBAPPTTR | |
| SCHEMBL14253556 | 0.89 | MAOB (0.80) | TOP2AEPHX2MAOBAPPTTR | |
| SCHEMBL5349280 | 0.88 | FDPS (0.72) | TOP2AEPHX2MAOBAPPTTR | |
| SCHEMBL5349276 | 0.88 | FDPS (0.72) | TOP2AEPHX2MAOBAPPTTR | |
| Ethyl Curcumin SCHEMBL8965263 | 0.88 | TOP2A (1.00) | TOP2AMAOBAPPALDH1A1CYP2D6 | |
| Ethyl Curcumin SCHEMBL8965258 | 0.88 | TOP2A (1.00) | TOP2AMAOBAPPALDH1A1CYP2D6 | |
| SCHEMBL27686673 | 0.86 | TOP2A (0.89) | TOP2AMAOBAPPALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591202-A | Ferulic acid derivative, preparation method and application | 西安医学院 | 2022-06-07 | — | — | CN | disclosed |