Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.58 |
| ▸ | ACHE | P22303 | 2/20 | 0.58 |
| ▸ | BACE1 | P56817 | 2/20 | 0.58 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | GPR183 | P32249 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | APLNR | P35414 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL970899 | 0.91 | ACHE (0.62) | BCHEACHEBACE1HTR2AMEN1 | |
| Water SCHEMBL22683358 | 0.90 | ACHE (0.61) | BCHEACHEBACE1HTR2AMEN1 | |
| Hydrochloric Acid SCHEMBL18587402 | 0.90 | ACHE (0.61) | BCHEACHEBACE1HTR2AMEN1 | |
| SCHEMBL20794625 | 0.89 | BCHE (0.57) | BCHEACHEBACE1HTR2AMEN1 | |
| SCHEMBL20794626 | 0.89 | BCHE (0.57) | BCHEACHEBACE1HTR2AMEN1 | |
| Piperazine SCHEMBL28117207 | 0.84 | ACHE (0.56) | BCHEACHEBACE1HTR2AMEN1 | |
| SCHEMBL5533747 | 0.83 | DRD4 (0.50) | BCHEACHEBACE1MEN1KMT2A | |
| SCHEMBL3712791 | 0.83 | ACHE (0.60) | BCHEACHEBACE1MEN1KMT2A | |
| SCHEMBL20794851 | 0.82 | BCHE (0.60) | BCHEACHEBACE1MEN1KMT2A | |
| SCHEMBL13911887 | 0.82 | BCHE (0.56) | BCHEACHEBACE1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106518751-B | Method for preparing pimavanserin | 江苏先声药业有限公司 | 2021-05-04 | — | — | CN | disclosed |