Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 5/20 | 0.47 |
| ▸ | BACE1 | P56817 | 5/20 | 0.47 |
| ▸ | BCHE | P06276 | 3/20 | 0.47 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.45 |
| ▸ | FABP6 | P51161 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29056584 | 0.86 | HDAC1 (0.59) | DRD4HDAC1KMT2AHRH3SSTR3 | |
| SCHEMBL4214296 | 0.86 | CHKA (0.50) | DRD4HDAC1KMT2AMEN1ALDH1A1 | |
| Oxalic Acid SCHEMBL28548418 | 0.83 | BCHE (0.58) | CARM1PRMT6KMT2AHRH3ACHE | |
| SCHEMBL791504 | 0.82 | CHEK1 (0.54) | HDAC1KMT2ASSTR3MEN1RAB9A | |
| SCHEMBL4210239 | 0.81 | CARM1 (0.49) | CARM1PRMT6KMT2AHRH3ACHE | |
| SCHEMBL21089268 | 0.81 | HDAC1 (0.72) | HDAC1KMT2AHRH3SSTR3MEN1 | |
| SCHEMBL14487967 | 0.81 | ACHE (0.50) | DRD4CARM1PRMT6KMT2AACHE | |
| SCHEMBL8081164 | 0.81 | ACHE (0.68) | CARM1PRMT6KMT2AACHEBACE1 | |
| SCHEMBL27709142 | 0.80 | BCHE (0.49) | DRD4ACHEBACE1BCHE | |
| SCHEMBL21235736 | 0.80 | CARM1 (0.50) | CARM1PRMT6KMT2AHRH3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1787984-A2 | AZACYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF SEROTONIN RELATED DISEASES | Arcadia Pharmaceuticals Inc. (US) | 2007-05-23 | — | — | EP | disclosed |