Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | GLA | P06280 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAPDH | P04406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19141923 | 0.81 | ACHE (0.47) | NPC1MAPTPOLBTSHRRAB9A | |
| SCHEMBL28554333 | 0.80 | NPC1 (0.48) | NPC1POLBCA12CA9FLT3 | |
| SCHEMBL20870968 | 0.73 | CA2 (0.39) | NPC1MAPTPOLBCA12CA9 | |
| SCHEMBL20870962 | 0.73 | NPC1 (0.34) | NPC1MAPTPOLBCA12CA9 | |
| Hydrochloric Acid SCHEMBL5617709 | 0.73 | FLT3 (0.41) | NPC1POLBCA12CA9FLT3 | |
| SCHEMBL9689456 | 0.72 | MAPT (0.62) | MAPTPOLBLMNATDP1 | |
| SCHEMBL14541242 | 0.72 | CA12 (0.58) | NPC1MAPTPOLBCA12CA9 | |
| SCHEMBL23218521 | 0.71 | MAPT (0.41) | MAPTPOLBCA12CA9CA2 | |
| SCHEMBL23115220 | 0.70 | MAPT (0.68) | MAPTPOLBTSHRLMNASMN1; SMN2 | |
| SCHEMBL11798029 | 0.69 | MAPT (0.51) | MAPTPOLBTSHRLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109574945-B | Isoxazoline derivatives and their use in agriculture | 东莞市东阳光农药研发有限公司 | 2021-04-20 | — | — | CN | disclosed |