Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21753071 | 0.87 | MAPT (0.37) | POLBALDH1A1MAPTHPGDADRB1 | |
| Hydrochloric Acid SCHEMBL23044940 | 0.86 | KCNJ1 (0.43) | ALDH1A1HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27807066 | 0.85 | ALDH1A1 (0.40) | POLBALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL5742221 | 0.81 | OPRD1 (0.46) | OPRD1ALDH1A1HTTSMN1; SMN2NPC1 | |
| SCHEMBL21751755 | 0.80 | OPRD1 (0.45) | OPRD1ALDH1A1HTTGLASMN1; SMN2 | |
| SCHEMBL28881539 | 0.80 | OPRD1 (0.45) | OPRD1ALDH1A1HTTSMN1; SMN2NPC1 | |
| SCHEMBL23165692 | 0.80 | OPRD1 (0.45) | OPRD1ALDH1A1HTTGLASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28932661 | 0.79 | OPRD1 (0.44) | OPRD1ALDH1A1HTTGLASMN1; SMN2 | |
| SCHEMBL2113970 | 0.77 | SLC6A2 (0.50) | ADRB1SIRT6 | |
| SCHEMBL27898912 | 0.74 | HTR2C (0.43) | ALDH1A1MEN1KMT2ASMN1; SMN2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728910-B | Pyrazole derivative for FGFR inhibitor and preparation method thereof | 上海奕拓医药科技有限责任公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-114728910-A | Pyrazole derivatives for FGFR inhibitor and preparation method thereof | 上海奕拓医药科技有限责任公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-112441980-A | Pyrazole derivatives for FGFR inhibitor and preparation method thereof | 上海奕拓医药科技有限责任公司 | 2021-03-05 | — | — | CN | disclosed |