Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19687283 | 0.85 | HTT (0.62) | HTTLMNACYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL28546791 | 0.72 | HSD17B10 (0.58) | HTTLMNACYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL22020816 | 0.71 | ALDH1A1 (0.56) | LMNANPSR1ALDH1A1L3MBTL1TP53 | |
| SCHEMBL1936057 | 0.71 | HTT (0.86) | HTTLMNACYP2C19CYP1A2NPSR1 | |
| SCHEMBL29310610 | 0.70 | MAPT (0.47) | HTTLMNACYP2C19CYP1A2NPSR1 | |
| SCHEMBL19691025 | 0.70 | HTT (0.65) | HTTLMNACYP2C19CYP1A2NPSR1 | |
| SCHEMBL21144023 | 0.69 | SMN1; SMN2 (0.58) | HTTLMNACYP1A2ALDH1A1L3MBTL1 | |
| SCHEMBL28556791 | 0.69 | NOTUM (0.45) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11174391 | 0.68 | HTT (1.00) | HTTLMNACYP2C19CYP1A2NPSR1 | |
| SCHEMBL15980614 | 0.68 | NOS3 (0.57) | LMNACYP2C19ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112679555-A | Broad-spectrum divalent platinum complex and preparation method and application thereof | 南京工业大学 | 2021-04-20 | — | — | CN | claimed |
| CN-112679555-B | Broad-spectrum divalent platinum complex and preparation method and application thereof | 南京工业大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-112679555-A | Broad-spectrum divalent platinum complex and preparation method and application thereof | 南京工业大学 | 2021-04-20 | — | — | CN | disclosed |