Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28911437 | 0.89 | TP53 (0.47) | ALDH1A1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL4975316 | 0.84 | SMN1; SMN2 (0.52) | MAPTKMT2ALMNASMN1; SMN2CD274 | |
| SCHEMBL14224679 | 0.82 | KDM4E (0.60) | ALDH1A1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL21588984 | 0.82 | MAPT (0.55) | ALDH1A1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL28538284 | 0.80 | GAA (0.60) | ALDH1A1KMT2ALMNAMEN1SMN1; SMN2 | |
| SCHEMBL16134077 | 0.80 | TP53 (0.47) | ALDH1A1MAPTKMT2ALMNASMN1; SMN2 | |
| SCHEMBL5238748 | 0.80 | ALDH1A1 (0.56) | ALDH1A1MAPTKMT2AKCNJ1LMNA | |
| SCHEMBL6202441 | 0.78 | MAPT (0.54) | ALDH1A1MAPTKMT2AKCNJ1LMNA | |
| SCHEMBL22571323 | 0.78 | CD274 (0.61) | ALDH1A1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL7143311 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MAPTKMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108264511-B | Heterocyclic derivative, preparation method thereof and application thereof in medicine | 浙江海正药业股份有限公司 | 2021-04-13 | — | — | CN | disclosed |