Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CRHBP | P24387 | 2/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28558130 | 0.90 | MAPT (0.41) | MAPTGAAHCAR3ALDH1A1CRHBP | |
| SCHEMBL28548656 | 0.90 | MAPT (0.42) | MAPTGAAHCAR3ALDH1A1CRHBP | |
| SCHEMBL21158729 | 0.85 | TSHR (0.35) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL28912725 | 0.84 | MAPT (0.44) | MAPTGAAHCAR3ALDH1A1CRHBP | |
| SCHEMBL28548642 | 0.83 | MAPT (0.45) | MAPTGAAHCAR3ALDH1A1CRHBP | |
| SCHEMBL28556407 | 0.82 | MAPT (0.36) | MAPTGAAHCAR3ALDH1A1CRHBP | |
| SCHEMBL28556386 | 0.82 | MAPT (0.40) | MAPTGAAHCAR3ALDH1A1CRHBP | |
| SCHEMBL21156963 | 0.81 | LMNA (0.40) | MAPTGAAALDH1A1CRHBPCRHR2 | |
| SCHEMBL28553322 | 0.80 | KMT2A (0.46) | MAPTGAAHCAR3ALDH1A1CRHBP | |
| SCHEMBL28552449 | 0.80 | PDE4D (0.47) | MAPTGAAHCAR3ALDH1A1CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110016021-B | Immunomodulator | 成都先导药物开发股份有限公司 | 2021-05-07 | — | — | CN | disclosed |