Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | BPTF | Q12830 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21158913 | 0.91 | USP2 (0.33) | TSHRALDH1A1SMN1; SMN2CREBBPPTGER4 | |
| SCHEMBL21158909 | 0.89 | IRAK4 (0.38) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28548646 | 0.85 | MAPT (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL22121045 | 0.84 | TSHR (0.43) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL21158643 | 0.82 | STING1 (0.42) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL21158654 | 0.81 | PARP15 (0.43) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28560847 | 0.81 | CHEK2 (0.38) | — | |
| SCHEMBL21158981 | 0.80 | TSHR (0.34) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL21158926 | 0.77 | SMN1; SMN2 (0.36) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL21158773 | 0.77 | PDE4D (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110016021-B | Immunomodulator | 成都先导药物开发股份有限公司 | 2021-05-07 | — | — | CN | disclosed |
| WO-2019134707-A1 | IMMUNOMODULATOR | 成都先导药物开发股份有限公司 | 2019-07-11 | — | — | WO | disclosed |