Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 8/20 | 0.85 |
| ▸ | F2 | P00734 | 1/20 | 0.85 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10738426 | 0.92 | NOTUM (1.00) | NOTUMF2MAPTKCNJ1ALDH1A1 | |
| SCHEMBL12615985 | 0.82 | NOTUM (0.78) | NOTUMF2MAPTKCNJ1ALDH1A1 | |
| SCHEMBL11118984 | 0.76 | NOTUM (0.64) | NOTUMF2MAPTKCNJ1ALDH1A1 | |
| SCHEMBL16083829 | 0.73 | NOTUM (0.77) | NOTUMF2MAPTKCNJ1ALDH1A1 | |
| SCHEMBL1163779 | 0.72 | NOTUM (0.64) | NOTUMF2MAPTKCNJ1ALDH1A1 | |
| SCHEMBL11711879 | 0.72 | NOTUM (0.64) | NOTUMF2MAPTKCNJ1ALDH1A1 | |
| SCHEMBL311636 | 0.72 | MAPT (1.00) | NOTUMF2MAPTKCNJ1ALDH1A1 | |
| SCHEMBL82595 | 0.72 | MAPT (0.69) | NOTUMF2MAPTKCNJ1ALDH1A1 | |
| SCHEMBL4582384 | 0.72 | NOTUM (0.64) | NOTUMF2MAPTKCNJ1ALDH1A1 | |
| SCHEMBL17993966 | 0.72 | NOTUM (0.64) | NOTUMF2MAPTKCNJ1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112608303-B | Piperazine intermediate, preparation method and application thereof | 华南理工大学 | 2021-10-26 | — | — | CN | claimed |
| CN-112608303-A | Piperazine intermediate, preparation method and application thereof | 华南理工大学 | 2021-04-06 | — | — | CN | claimed |
| CN-112608303-B | Piperazine intermediate, preparation method and application thereof | 华南理工大学 | 2021-10-26 | — | — | CN | disclosed |
| CN-112608303-A | Piperazine intermediate, preparation method and application thereof | 华南理工大学 | 2021-04-06 | — | — | CN | disclosed |