SCHEMBL1163779

SCHEMBL1163779

Nc1ccc(-n2cnnn2)cc1

nearest known ligand 0.64

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 5/20 0.64
MAPT P10636 2/20 0.64
F2 P00734 1/20 0.64
KCNJ1 P48048 3/20 0.60
ALDH1A1 P00352 4/20 0.58
LMNA P02545 1/20 0.58
HTT P42858 1/20 0.58
POLB P06746 1/20 0.51
BLM P54132 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
HPGD P15428 1/20 0.47
RAB9A P51151 1/20 0.46
KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12615985 0.89 NOTUM (0.78) NOTUMMAPTF2KCNJ1ALDH1A1
SCHEMBL17993966 0.78 NOTUM (0.64) NOTUMMAPTF2KCNJ1ALDH1A1
SCHEMBL11711879 0.78 NOTUM (0.64) NOTUMMAPTF2KCNJ1ALDH1A1
SCHEMBL10738426 0.78 NOTUM (1.00) NOTUMMAPTF2KCNJ1ALDH1A1
SCHEMBL11831417 0.78 NOTUM (0.64) NOTUMMAPTF2KCNJ1ALDH1A1
SCHEMBL4582384 0.78 NOTUM (0.64) NOTUMMAPTF2KCNJ1ALDH1A1
SCHEMBL311636 0.78 MAPT (1.00) NOTUMMAPTF2KCNJ1ALDH1A1
SCHEMBL82595 0.78 MAPT (0.69) NOTUMMAPTF2KCNJ1ALDH1A1
SCHEMBL11118984 0.78 NOTUM (0.64) NOTUMMAPTF2KCNJ1ALDH1A1
SCHEMBL8485436 0.78 KCNJ1 (0.66) NOTUMMAPTF2KCNJ1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250354659-A1 SYSTEM AND METHOD FOR STORING LIQUIDS HAVING LOW LATENT HEAT OF VAPORIZATION NUOVO PIGNONE TECNOLOGIE – S R L (IT) 2025-11-20 US claimed
WO-2025238576-A1 SYSTEM AND METHOD FOR STORING LIQUIDS HAVING LOW LATENT HEAT OF VAPORIZATION Nuovo Pignone Tecnologie – S.r.l. (IT) 2025-11-20 WO claimed
CN-117720789-B Low-smoke halogen-free fireproof flame-retardant power cable and preparation method thereof 天津市天鸿祥线缆有限公司 2024-04-12 CN claimed
CN-117720789-A Low-smoke halogen-free fireproof flame-retardant power cable and preparation method thereof 天津市天鸿祥线缆有限公司 2024-03-19 CN claimed
US-20070102076-A1 Gas-producing mixtures DELPHI TECHNOLOGIES, INC. (US) 2007-05-10 US claimed
CN-1183758-A Gas-generating mixture DYNAMIT NOBEL AG (DE) 1998-06-03 CN claimed
EP-0809616-A1 GAS-GENERATING MIXTURES Dynamit Nobel GmbH Explosivstoff- und Systemtechnik (DE) 1997-12-03 EP claimed
WO-1996026169-A1 GAS-GENERATING MIXTURES DYNAMIT NOBEL GMBH (DE) 1996-08-29 WO claimed
WO-2026102259-A1 SYSTEM AND METHOD FOR TARGETED GAS DESORPTION FROM SORBENTS VIA AN EDUCTOR PUMP MECHANISM MOSAIC MATERIALS, INC. (US) 2026-05-15 WO disclosed
US-20260131275-A1 SYSTEM AND METHOD FOR TARGETED GAS DESORPTION FROM SORBENTS VIA AN EDUCTOR PUMP MECHANISM MOSAIC MAT INC (US) 2026-05-14 US disclosed
WO-2025238576-A1 SYSTEM AND METHOD FOR STORING LIQUIDS HAVING LOW LATENT HEAT OF VAPORIZATION Nuovo Pignone Tecnologie – S.r.l. (IT) 2025-11-20 WO disclosed
US-20250354659-A1 SYSTEM AND METHOD FOR STORING LIQUIDS HAVING LOW LATENT HEAT OF VAPORIZATION NUOVO PIGNONE TECNOLOGIE – S R L (IT) 2025-11-20 US disclosed
US-20240327452-A1 Bile Acid Derivatives as FXR/TGR5 Agonists and Methods of Use Thereof ENANTA PHARM INC (US) 2024-10-03 US disclosed
US-11958879-B2 Bile acid derivatives as FXR/TGR5 agonists and methods of use thereof ENANTA PHARMACEUTICALS, INC. (US) 2024-04-16 US disclosed
EP-1063228-A1 CYCLOALKENE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND USE Takeda Chemical Industries, Ltd. (JP) 2000-12-27 EP disclosed
US-6020357-A CARDIOVASCULAR DISORDERS; ANTCOAGULANTS DUPONT PHARMACEUTICALS COMPANY (US) 2000-02-01 US disclosed
EP-0884311-A2 Triazole Derivatives and their production Takeda Chemical Industries, Ltd. (JP) 1998-12-16 EP disclosed
CN-1183758-A Gas-generating mixture DYNAMIT NOBEL AG (DE) 1998-06-03 CN disclosed
EP-0809616-A1 GAS-GENERATING MIXTURES Dynamit Nobel GmbH Explosivstoff- und Systemtechnik (DE) 1997-12-03 EP disclosed
WO-1996026169-A1 GAS-GENERATING MIXTURES DYNAMIT NOBEL GMBH (DE) 1996-08-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11958879-B2 Bile acid derivatives as FXR/TGR5 agonists and methods of use thereof GPBAR1, NR1H4, SLC10A1 NOTUM 1220/4885MAPT 1709/4885F2 3477/4885
US-20260131275-A1 SYSTEM AND METHOD FOR TARGETED GAS DESORPTION FROM SORBENTS VIA AN EDUCTOR PUMP MECHANISM EXOSC9, EXOSC4, EXOSC5 NOTUM 1839/4885MAPT 3402/4885F2 672/4885
US-20240327452-A1 Bile Acid Derivatives as FXR/TGR5 Agonists and Methods of Use Thereof GPBAR1, NR1H4, SLC10A1 NOTUM 1220/4885MAPT 1709/4885F2 3477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.