Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 7/20 | 0.45 |
| ▸ | CTSK | P43235 | 7/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.44 |
| ▸ | ACACB | O00763 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12765945 | 1.00 | PPARG (0.49) | PPARGPPARALDHAITGB3ITGA2B | |
| SCHEMBL27484314 | 0.88 | PPARG (0.50) | PPARGPPARALDHAITGB3ITGA2B | |
| SCHEMBL20415660 | 0.87 | CTSL (0.53) | PPARGPPARALDHAITGB3ITGA2B | |
| SCHEMBL28912771 | 0.87 | CTSL (0.53) | PPARGPPARALDHAITGB3ITGA2B | |
| SCHEMBL1519747 | 0.85 | CTSS (0.58) | PPARGPPARACTSSCTSKCTSB | |
| SCHEMBL1519749 | 0.85 | CTSS (0.58) | PPARGPPARACTSSCTSKCTSB | |
| SCHEMBL17865714 | 0.85 | CTSS (0.58) | PPARGPPARACTSSCTSKCTSB | |
| SCHEMBL2550244 | 0.84 | PPARG (0.50) | PPARGPPARAITGB3ITGA2BCTSS | |
| SCHEMBL12766383 | 0.84 | PPARG (0.50) | PPARGPPARAITGB3ITGA2BCTSS | |
| SCHEMBL20397698 | 0.83 | PPARG (0.52) | PPARGPPARALDHAITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107848962-B | Urea derivative or pharmacologically acceptable salt thereof | 杏林制药株式会社 | 2021-04-09 | — | — | CN | disclosed |