Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28557357 | 0.89 | AURKB (0.49) | ADORA3ADORA2ATNIKMAPTAURKA | |
| SCHEMBL28570362 | 0.87 | RET (0.43) | ACHEADORA3ADORA2AMAPTTP53 | |
| SCHEMBL28022063 | 0.86 | SMN1; SMN2 (0.42) | MAPTTP53AURKAAURKBLMNA | |
| SCHEMBL28021607 | 0.86 | SLC2A1 (0.44) | ACHESLC2A1TNIKIDO1MAPT | |
| SCHEMBL28556178 | 0.82 | AURKA (0.39) | MAPTTP53AURKAAURKBPOLB | |
| SCHEMBL2204695 | 0.82 | AURKB (0.60) | SLC2A1ADORA3ADORA2ATNIKMAPT | |
| SCHEMBL28022078 | 0.81 | PKM (0.44) | MAPTAURKAAURKBLMNAPOLB | |
| SCHEMBL28021591 | 0.80 | AURKB (0.51) | ADORA3ADORA2AMAPTGSK3BAURKA | |
| SCHEMBL28548957 | 0.80 | ADORA1 (0.44) | ADORA3ADORA2AMAPTAURKAAURKB | |
| SCHEMBL28022048 | 0.79 | AURKA (0.46) | MAPTAURKAAURKBPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112755193-A | Method of treating malignancies with anti-tyrosine kinase inhibitors using dianhydrogalactitol or a derivative thereof | 德玛医药 | 2021-05-07 | — | — | CN | disclosed |