SCHEMBL28549833

SCHEMBL28549833

[CH2]C[Si](c1ccccc1)(c1ccccc1)C(C)(C)C.[LiH]

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.31
SLC6A2 P23975 1/20 0.31
ATM Q13315 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL40797 0.98 TAAR1 (0.32) TAAR1SLC6A2ATMESR1ESR2
SCHEMBL14770816 0.77 TP53 (0.35) TAAR1SLC6A2ATMESR1ESR2
SCHEMBL8701181 0.76 CYP2C19 (0.38) TAAR1SLC6A2ESR1ESR2
SCHEMBL2591855 0.76 TAAR1 (0.32) TAAR1SLC6A2ATMESR1ESR2
SCHEMBL2617396 0.76 TAAR1 (0.32) TAAR1SLC6A2ATMESR1ESR2
SCHEMBL22034849 0.75 MAPT (0.35) ATM
SCHEMBL28491406 0.74 MAPK1 (0.33) TAAR1SLC6A2ATMESR1ESR2
SCHEMBL8056864 0.72 MAPT (0.33) TAAR1SLC6A2
SCHEMBL11899211 0.72 TAAR1 (0.30) TAAR1SLC6A2
SCHEMBL506540 0.72 NR1H2 (0.33) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112625159-B Preparation method and application of catalyst for synthesizing hydroxyl-terminated trans-1, 4-polyisoprene polymer 青岛竣翔科技有限公司 2022-05-10 CN claimed
CN-112625159-A Preparation method and application of catalyst for synthesizing hydroxyl-terminated trans-1, 4-polyisoprene polymer 青岛竣翔科技有限公司 2021-04-09 CN claimed