Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28549833 | 0.98 | TAAR1 (0.31) | TAAR1SLC6A2ATMESR1ESR2 | |
| SCHEMBL14770816 | 0.79 | TP53 (0.35) | TAAR1SLC6A2ATMESR1ESR2 | |
| SCHEMBL8701181 | 0.77 | CYP2C19 (0.38) | TAAR1SLC6A2ESR1ESR2 | |
| SCHEMBL2591855 | 0.77 | TAAR1 (0.32) | TAAR1SLC6A2ATMESR1ESR2 | |
| SCHEMBL2617396 | 0.77 | TAAR1 (0.32) | TAAR1SLC6A2ATMESR1ESR2 | |
| SCHEMBL22034849 | 0.77 | MAPT (0.35) | ATMMAPK1 | |
| SCHEMBL28491406 | 0.76 | MAPK1 (0.33) | TAAR1SLC6A2ATMESR1ESR2 | |
| SCHEMBL8056864 | 0.74 | MAPT (0.33) | TAAR1SLC6A2 | |
| SCHEMBL11899211 | 0.74 | TAAR1 (0.30) | TAAR1SLC6A2 | |
| SCHEMBL506540 | 0.74 | NR1H2 (0.33) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2668176-B1 | A NOVEL PROCESS FOR SYNTHESIS OF POLYPHENOLS | SPHAERA PHARMA PTE LTD (SG) | 2017-05-17 | — | — | EP | claimed |
| US-9428482-B2 | Process for synthesis of polyphenols | SPHAERA PHARMA PTE. LTD. (SG) | 2016-08-30 | — | — | US | claimed |
| CN-103582635-A | A novel process for synthesis of polyphenols | SPHAERA PHARMA PRIVATE LTD | 2014-02-12 | — | — | CN | claimed |
| US-20140031421-A1 | NOVEL PROCESS FOR SYNTHESIS OF POLYPHENOLS | SPHAERA PHARMA PTE. LTD. (SG) | 2014-01-30 | — | — | US | claimed |
| US-20240067599-A1 | IODOTYROSINE DERIVATIVES AND PROCESS FOR PREPARING IODOTYROSINE DERIVATIVES | ABX ADVANCED BIOCHEMICAL COMPOUNDS - BIOMEDIZINISCHE FORSCHUNGSREAGENZIEN GMBH (DE) | 2024-02-29 | — | — | US | disclosed |
| EP-4276092-A1 | COMPOUND LIBRARY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-15 | — | — | EP | disclosed |
| CN-116783160-A | Libraries of compounds | 中外制药株式会社 | 2023-09-19 | — | — | CN | disclosed |
| US-20230101138-A1 | POLYMER COMPOUND, METHOD FOR PRODUCING POLYMER COMPOUND, ADHESIVE COMPOSITION, CURED PRODUCT, METHOD FOR PRODUCING ADHESIVE COMPOSITION, AND METHOD FOR ADJUSTING ADHESION FORCE | NATIONAL INSTITUTE FOR MATERIALS SCIENCE (JP) | 2023-03-30 | — | — | US | disclosed |
| EP-4101870-A1 | POLYMER COMPOUND, METHOD FOR PRODUCING POLYMER COMPOUND, ADHESIVE COMPOSITION, CURED PRODUCT, METHOD FOR PRODUCING ADHESIVE COMPOSITION, AND METHOD FOR ADJUSTING ADHESIVE STRENGTH | National Institute for Materials Science (JP) | 2022-12-14 | — | — | EP | disclosed |
| CN-103582635-B | Method for synthesizing polyphenol | 斯法尔制药私人有限公司 | 2019-02-19 | — | — | CN | disclosed |
| EP-2668176-B1 | A NOVEL PROCESS FOR SYNTHESIS OF POLYPHENOLS | SPHAERA PHARMA PTE LTD (SG) | 2017-05-17 | — | — | EP | disclosed |
| US-9556140-B2 | Approach for synthesis of catechins | SPHAERA PHARMA PVT. LTD. (IN) | 2017-01-31 | — | — | US | disclosed |
| US-5719275-A | REACTING SILYL ENOL ETHER WITH AZETIDINONE DERIVATIVE TO FORM INTERMEDIATE FOR PENICILLIN-TYPE ANTIBIOTIC | SANKYO COMPANY, LIMITED (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5681951-A | REACTING PENICILLIN DERIVATIVE HAVING SULFINYL OR SULFONYL GROUP IN 2 POSITION WITH SUBSTITUTED MERCAPTAN IN PRESENCE OF SALT OF GROUP IIA OR IIIA ELEMENT | SANKYO COMPANY, LIMITED (JP) | 1997-10-28 | — | — | US | disclosed |
| EP-0801071-A1 | LEWIS X DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-10-15 | — | — | EP | disclosed |
| US-5614624-A | THIO SUBSTITUTED, ANTIBIOTICS, CHEMICAL INTERMEDIATES | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| US-5541317-A | PENICILLIN DERIVATIVES, CYCLIZATION OF ESTERS OR THIOESTERS | SANKYO COMPANY, LIMITED (JP) | 1996-07-30 | — | — | US | disclosed |
| EP-0714393-A1 | THIAZOLES AS ANTIVIRAL | PFIZER INC. (US) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995005378-A1 | ANTIVIRAL THIAZOLES | PFIZER INC. (US) | 1995-02-23 | — | — | WO | disclosed |
| EP-0587436-A1 | Process for preparing carbapenem and penem compounds and new compounds involved in that process | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140031421-A1 | NOVEL PROCESS FOR SYNTHESIS OF POLYPHENOLS | COMT, NQO1, SPR | TAAR1 4592/4885SLC6A2 4467/4885ATM 3606/4885 |
| US-20240067599-A1 | IODOTYROSINE DERIVATIVES AND PROCESS FOR PREPARING IODOTYROSINE DERIVATIVES | ALK, ALKBH3, INSR | TAAR1 22/4885SLC6A2 2493/4885ATM 2463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.