Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL506540 | 0.83 | NR1H2 (0.33) | CYP2C19HIF1AESR1ESR2TSHR | |
| SCHEMBL14770816 | 0.79 | TP53 (0.35) | ESR1ESR2TSHRMAPTTAAR1 | |
| SCHEMBL15564536 | 0.78 | NR1H2 (0.33) | HIF1AESR1ESR2TSHRNR1H2 | |
| SCHEMBL2591855 | 0.77 | TAAR1 (0.32) | ESR1ESR2TSHRTAAR1ALDH1A1 | |
| SCHEMBL2617396 | 0.77 | TAAR1 (0.32) | ESR1ESR2TAAR1ALDH1A1ALOX15 | |
| SCHEMBL40797 | 0.77 | TAAR1 (0.32) | ESR1ESR2TAAR1SLC6A2 | |
| SCHEMBL28534055 | 0.77 | ALDH1A1 (0.38) | CYP2C19HIF1AESR1ESR2NR1H2 | |
| SCHEMBL4591664 | 0.77 | CYP2C19 (0.42) | CYP2C19HIF1ACES2CES1MAPT | |
| SCHEMBL7344627 | 0.77 | MAPT (0.38) | CYP2C19HIF1ATSHRCES2CES1 | |
| SCHEMBL28549833 | 0.76 | TAAR1 (0.31) | ESR1ESR2TAAR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827868-A | Prostaglandin analogs | E. R. SQUIBB & SONS, INC. (US) | 1998-10-27 | — | — | US | disclosed |