SCHEMBL2855005

SCHEMBL2855005

CCCCCc1ccc(OC(=O)c2ccc(OCc3ccccc3)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
MAOB P27338 1/20 0.55
LTA4H P09960 1/20 0.55
EPHX2 P34913 1/20 0.55
HRH3 Q9Y5N1 1/20 0.54
NR4A1 P22736 1/20 0.54
NR4A2 P43354 1/20 0.54
NR4A3 Q92570 1/20 0.54
FFAR1 O14842 1/20 0.53
FFAR4 Q5NUL3 1/20 0.53
RXRA P19793 1/20 0.53
RXRB P28702 1/20 0.53
HDAC3 O15379 1/20 0.52
HDAC1 Q13547 1/20 0.52
HDAC2 Q92769 1/20 0.52
NCOR2 Q9Y618 1/20 0.52
SMPD1 P17405 1/20 0.52
PARP10 Q53GL7 1/20 0.51
THRB P10828 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8636620 0.99 SMPD1 (0.54) MAPTSMN1; SMN2MAOBLTA4HEPHX2
SCHEMBL10807328 0.99 SMPD1 (0.54) MAPTSMN1; SMN2MAOBLTA4HEPHX2
SCHEMBL9578641 0.99 SMPD1 (0.54) MAPTSMN1; SMN2MAOBLTA4HEPHX2
SCHEMBL4054835 0.91 MAOB (0.58) MAPTSMN1; SMN2MAOBNR4A1NR4A2
SCHEMBL8639906 0.90 LMNA (0.64) MAPTSMN1; SMN2MAOBNR4A1NR4A2
SCHEMBL27973868 0.89 NPC1 (0.64) MAPTSMN1; SMN2MAOBNPC1LMNA
SCHEMBL1934051 0.89 NPC1 (0.64) MAPTSMN1; SMN2MAOBNPC1LMNA
SCHEMBL27973867 0.89 NPC1 (0.64) MAPTSMN1; SMN2MAOBNPC1LMNA
SCHEMBL9578511 0.89 NPC1 (0.64) MAPTSMN1; SMN2MAOBNPC1LMNA
SCHEMBL9650867 0.89 NPC1 (0.64) MAPTSMN1; SMN2MAOBNPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7758932-B2 Liquid crystal display device and display apparatus RICOH COMPANY, LTD. (JP) 2010-07-20 US disclosed
EP-1972676-B1 Liquid crystal alignment film composition, liquid crystal device and display apparatus RICOH KK (JP) 2010-03-10 EP disclosed
US-7658979-B2 Liquid crystal alignment film composition, liquid crystal device and display apparatus RICOH COMPANY, LTD. (JP) 2010-02-09 US disclosed
US-20080305280-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY APPARATUS RICOH COMPANY, LTD. 2008-12-11 US disclosed
US-20080231785-A1 LIQUID CRYSTAL ALIGNMENT FILM COMPOSITION, LIQUID CRYSTAL DEVICE AND DISPLAY APPARATUS RICOH COMPANY, LTD. (JP) 2008-09-25 US disclosed
EP-1972676-A1 Liquid crystal alignment film composition, liquid crystal device and display apparatus Ricoh Company, Ltd. (JP) 2008-09-24 EP disclosed