SCHEMBL4054835

SCHEMBL4054835

CCCc1ccc(OC(=O)c2ccc(OCc3ccccc3)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.58
NR4A1 P22736 1/20 0.57
NR4A2 P43354 1/20 0.57
NR4A3 Q92570 1/20 0.57
FFAR1 O14842 1/20 0.57
FFAR4 Q5NUL3 1/20 0.57
RXRA P19793 1/20 0.57
RXRB P28702 1/20 0.57
SENP8 Q96LD8 1/20 0.57
SENP7 Q9BQF6 1/20 0.57
SENP6 Q9GZR1 1/20 0.57
HDAC3 O15379 1/20 0.55
HDAC1 Q13547 1/20 0.55
HDAC2 Q92769 1/20 0.55
NCOR2 Q9Y618 1/20 0.55
MAPT P10636 4/20 0.55
THRB P10828 1/20 0.55
PARP10 Q53GL7 1/20 0.55
SMN1; SMN2 Q16637 4/20 0.54
ALDH1A1 P00352 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9372119 0.97 RXRA (0.57) MAOBNR4A1NR4A2NR4A3FFAR1
SCHEMBL2855005 0.91 MAPT (0.55) MAOBNR4A1NR4A2NR4A3FFAR1
SCHEMBL10807328 0.90 SMPD1 (0.54) MAOBNR4A1NR4A2NR4A3FFAR1
SCHEMBL9578641 0.90 SMPD1 (0.54) MAOBNR4A1NR4A2NR4A3FFAR1
SCHEMBL8636620 0.90 SMPD1 (0.54) MAOBNR4A1NR4A2NR4A3FFAR1
SCHEMBL4057112 0.88 MAOB (0.60) MAOBNR4A1NR4A2NR4A3RXRA
SCHEMBL4057883 0.88 MAOB (0.60) MAOBNR4A1NR4A2NR4A3RXRA
SCHEMBL3760690 0.87 KMT2A (0.60) MAOBSENP8SENP7SENP6MAPT
SCHEMBL3771392 0.87 KMT2A (0.56) SENP8SENP7SENP6MAPTTHRB
SCHEMBL4811757 0.87 NR4A2 (0.70) MAOBNR4A1NR4A2NR4A3FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM MAOB 3766/4885NR4A1 78/4885NR4A2 710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.