SCHEMBL28550384

SCHEMBL28550384

COc1cc(/C=N/O)cc2c1OC(C)(C)C2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.40
KMT2A Q03164 6/20 0.39
ALDH1A1 P00352 4/20 0.39
MEN1 O00255 4/20 0.39
HTT P42858 2/20 0.39
HPGD P15428 1/20 0.39
CYP1A2 P05177 2/20 0.37
CYP3A4 P08684 2/20 0.37
CYP2C19 P33261 2/20 0.37
PKM P14618 1/20 0.37
MAPK1 P28482 1/20 0.37
MAPT P10636 4/20 0.37
GAA P10253 1/20 0.37
LMNA P02545 2/20 0.36
NPC1 O15118 3/20 0.35
RAB9A P51151 3/20 0.35
NFKB1 P19838 2/20 0.34
NFKB2 Q00653 2/20 0.34
RELA Q04206 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5784052 0.82 KMT2A (0.41) KMT2AALDH1A1LMNANPC1RAB9A
SCHEMBL5787117 0.81 ALDH1A1 (0.41) KMT2AALDH1A1HPGDLMNANPC1
SCHEMBL5784331 0.78 KMT2A (0.39) KMT2AALDH1A1HTTLMNANPC1
SCHEMBL5783546 0.76 VCP (0.50) KMT2AALDH1A1MEN1HTTPKM
SCHEMBL5783541 0.76 VCP (0.50) KMT2AALDH1A1MEN1HTTPKM
SCHEMBL30522175 0.76 KMT2A (0.38) KMT2AALDH1A1LMNANPC1RAB9A
SCHEMBL5783529 0.76 KMT2A (0.34) KMT2AMEN1HTTHPGDCYP3A4
SCHEMBL5786354 0.76 EGFR (0.40) KMT2AALDH1A1MEN1HPGDCYP1A2
SCHEMBL5786358 0.76 EGFR (0.40) KMT2AALDH1A1MEN1HPGDCYP1A2
SCHEMBL30522177 0.75 KMT2A (0.42) KMT2AALDH1A1HTTMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112661732-A Furanol derivative and preparation method and application thereof 湖南加法检测有限公司 2021-04-16 CN disclosed