Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.76 |
| ▸ | TSHR | P16473 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.46 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | PPARD | Q03181 | 7/20 | 0.46 |
| ▸ | PPARA | Q07869 | 7/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14010816 | 1.00 | ALDH1A1 (0.76) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL3628969 | 1.00 | ALDH1A1 (0.76) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL14010968 | 1.00 | ALDH1A1 (0.76) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL12906731 | 1.00 | ALDH1A1 (0.76) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL8262823 | 1.00 | ALDH1A1 (0.76) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL8269056 | 1.00 | ALDH1A1 (0.76) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL9007918 | 1.00 | ALDH1A1 (0.76) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL12592828 | 1.00 | ALDH1A1 (0.76) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL23191004 | 0.98 | ALDH1A1 (0.72) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL5351480 | 0.98 | ALDH1A1 (0.72) | ALDH1A1TSHRLMNANFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112724088-B | Uracil compound and anti-tumor application thereof | 中国医学科学院医药生物技术研究所 | 2022-04-29 | — | — | CN | disclosed |
| CN-112724088-A | Uracil compound and anti-tumor application thereof | 中国医学科学院医药生物技术研究所 | 2021-04-30 | — | — | CN | disclosed |
| CN-112618550-A | Antineoplastic uracil compound and lipid composition thereof | 中国医学科学院医药生物技术研究所 | 2021-04-09 | — | — | CN | disclosed |