Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.76 |
| ▸ | TSHR | P16473 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.46 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | PPARD | Q03181 | 7/20 | 0.46 |
| ▸ | PPARA | Q07869 | 7/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14010816 | 1.00 | ALDH1A1 (0.76) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL14010968 | 1.00 | ALDH1A1 (0.76) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL12906731 | 1.00 | ALDH1A1 (0.76) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL8262823 | 1.00 | ALDH1A1 (0.76) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL8269056 | 1.00 | ALDH1A1 (0.76) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL9007918 | 1.00 | ALDH1A1 (0.76) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL12592828 | 1.00 | ALDH1A1 (0.76) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL28550528 | 1.00 | ALDH1A1 (0.76) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL23191004 | 0.98 | ALDH1A1 (0.72) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL5351480 | 0.98 | ALDH1A1 (0.72) | ALDH1A1TSHRLMNANFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613343-B1 | INSULIN POLYPEPTIDE-OLIGOMER CONJUGATES, PROINSULIN POLYPEPTIDE-OLIGOMER CONJUGATES AND METHODS OF SYNTHESIZING SAME | BIOCON LTD (IN) | 2016-12-07 | — | — | EP | disclosed |
| EP-1404178-B1 | MIXTURES OF INSULIN DRUG-OLIGOMER CONJUGATES COMPRISING POLYALKYLENE GLYCOL, USES THEREOF, AND METHODS OF MAKING SAME | BIOCON LTD (IN) | 2016-01-20 | — | — | EP | disclosed |
| EP-1404360-B1 | MONODISPERSE MIXTURES OF CALCITONIN DRUG-OLIGOMER CONJUGATES COMPRISING POLYETHYLENE GLYCOL, USES THEREOF, AND METHODS OF MAKING SAME | BIOCON LTD (IN) | 2010-01-06 | — | — | EP | disclosed |
| US-20090281023-A9 | Mixtures Of Calcitonin Drug-Oligomer Conjugates And Methods Of Use In Pain Treatment | NOBEX CORPORATION (US) | 2009-11-12 | — | — | US | disclosed |
| US-7611864-B2 | Proinsulin polypeptide-oligomer conjugates | BIOCON LIMITED (IN) | 2009-11-03 | — | — | US | disclosed |
| EP-1430082-B1 | METHODS OF SYNTHESIZING INSULIN POLYPEPTIDE-OLIGOMER CONJUGATES, AND PROINSULIN POLYPEPTIDE-OLIGOMER CONJUGATES AND METHODS OF SYNTHESIZING SAME | BIOCON LTD (IN) | 2009-10-28 | — | — | EP | disclosed |
| US-7470663-B2 | Mixtures of insulin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same | BIOCON LIMITED (IN) | 2008-12-30 | — | — | US | disclosed |
| US-20080312135-A1 | MIXTURES OF DRUG-OLIGOMER CONJUGATES COMPRISING POLYETHYLENE GLYCOL, USES THEREOF, AND METHODS OF MAKING SAME | EKWURIBE NNOCHIRI N | 2008-12-18 | — | — | US | disclosed |
| US-7368260-B2 | Methods of synthesizing insulin polypeptide-oligomer conjugates, and proinsulin polypeptide-oligomer conjugates and methods of synthesizing same | BIOCON LIMITED (IN) | 2008-05-06 | — | — | US | disclosed |
| EP-1613343-A4 | INSULIN POLYPEPTIDE-OLIGOMER CONJUGATES, PROINSULIN POLYPEPTIDE-OLIGOMER CONJUGATES AND METHODS OF SYNTHESIZING SAME | BIOCON LTD (IN) | 2008-03-05 | — | — | EP | disclosed |
| US-20030060606-A1 | Mixtures of calcitonin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same | BIOCON LIMITED (IN) | 2003-03-27 | — | — | US | disclosed |
| WO-2003022210-A2 | PHARMACEUTICAL COMPOSITIONS OF DRUG-OLIGOMER CONJUGATES AND METHODS OF TREATING DISEASES THEREWITH | NOBEX CORPORATION (US) | 2003-03-20 | — | — | WO | disclosed |
| WO-2003022996-A2 | METHODS OF SYNTHESIZING INSULIN POLYPEPTIDE-OLIGOMER CONJUGATES, AND PROINSULIN POLYPEPTIDE-OLIGOMER CONJUGATES AND METHODS OF SYNTHESIZING SAME | NOBEX CORPORATION (US) | 2003-03-20 | — | — | WO | disclosed |
| WO-2003022208-A2 | PHARMACEUTICAL COMPOSITIONS OF INSULIN DRUG-OLIGOMER CONJUGATES AND METHODS OF TREATING DISEASES THEREWITH | NOBEX CORPORATION (US) | 2003-03-20 | — | — | WO | disclosed |
| US-20030027995-A1 | Mixtures of growth hormone drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same | BIOCON LIMITED (IN) | 2003-02-06 | — | — | US | disclosed |
| US-20030027748-A1 | Mixtures of insulin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same | BIOCON LIMITED (IN) | 2003-02-06 | — | — | US | disclosed |
| WO-2002098452-A1 | MIXTURES OF GROWTH HORMONE DRUG-OLIGOMER CONJUGATES COMPROMISING POLYALKYLENE GLYCOL, USES THEREOF, AND METHODS OF MAKING SAME | NOBEX CORPORATION (US) | 2002-12-12 | — | — | WO | disclosed |
| WO-2002098446-A1 | MIXTURES OF DRUG-OLIGOMER CONJUGATES COMPRISING POLYALKYLENE GLYCOL, USES THEREOF, AND METHODS OF MAKING SAME | NOBEX CORPORATION (US) | 2002-12-12 | — | — | WO | disclosed |
| WO-2002098451-A1 | MIXTURES OF CALCITONIN DRUG-OLIGOMER CONJUGATES COMPRISING POLYALKYLENE GLYCOL, USES THEREOF, AND METHODS OF MAKING SAME | NOBEX CORPORATION (US) | 2002-12-12 | — | — | WO | disclosed |
| WO-2002098232-A1 | MIXTURES OF INSULIN DRUG-OLIGOMER CONJUGATES COMPRISING POLYALKYLENE GLYCOL, USES THEREOF, AND METHODS OF MAKING SAME | NOBEX CORPORATION (US) | 2002-12-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281023-A9 | Mixtures Of Calcitonin Drug-Oligomer Conjugates And Methods Of Use In Pain Treatment | CALCB, CALCR, CALCA | ALDH1A1 3849/4885TSHR 1949/4885LMNA 1468/4885 |
| US-20030027748-A1 | Mixtures of insulin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same | IAPP, SI, IDE | ALDH1A1 3570/4885TSHR 1412/4885LMNA 2643/4885 |
| US-20030027995-A1 | Mixtures of growth hormone drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same | GHRHR, GHSR, GHITM | ALDH1A1 3621/4885TSHR 43/4885LMNA 3948/4885 |
| US-20080312135-A1 | MIXTURES OF DRUG-OLIGOMER CONJUGATES COMPRISING POLYETHYLENE GLYCOL, USES THEREOF, AND METHODS OF MAKING SAME | SI, SLC10A2, FABP2 | ALDH1A1 1943/4885TSHR 3744/4885LMNA 3331/4885 |
| US-20030060606-A1 | Mixtures of calcitonin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same | CALCB, CALCR, CALCA | ALDH1A1 3603/4885TSHR 1403/4885LMNA 1453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.